Worcester Business Journal

Book of Lists 2018

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wbjournal.com | Book of Lists 2018 | Worcester Business Journal 75 M A N U F A C T U R I N G & T E C H N O L O G Y F O C U S Top biomedical companies Ranked by number of local employees Company Local employees Products Head of company Year founded 1 Sanofi Genzyme (a) 15 Pleasant St. Connector, Framingham 01701 508-872-8400 • www.sanofigenzyme.com 1,800 Biotechnology Bill Sibold executive vice president 1981 2 Boston Scientific Corp. 300 Boston Scientific Way, Marlborough 01752 508-683-5670 • www.bostonscientific.com 1,700 Medical devices Michael F. Mahoney president & CEO 1979 3 Waters Corp. 34 Maple St., Milford 01757 508-482-2000 • www.waters.com 1,500 Analytical science technologies Christopher J. O'Connell chairman, president & CEO 1958 4 Quest Diagnostics Inc. 200 Forest St., Marlborough 01752 866-697-8378 • www.questdiagnostics.com 1,450 (b) Diagnostic information services Steve Rusckowski president & CEO 1967 5 Hologic Inc. 250 Campus Drive, Marlborough 01752 508-263-2900 • www.hologic.com 1,245 Medical devices Stephen P. MacMillan president & CEO 1985 6 Integrated Genetics (LabCorp) 3400 Computer Drive, Westborough 01581 508-898-9001 • www.integratedgenetics.com ~1,000 (c) Healthcare diagnostics David P. King president & CEO 1991 7 AbbVie Inc. 100 Research Drive, Worcester 01605 508-849-2500 • www.abbvie.com 900 Biopharmaceutical therapies targeted at immunology, oncology, virology and neuroscience Richard A. Gonzalez chairman & CEO 2013 8 Bristol-Myers Squibb Co. 38 Jackson Road, Devens 01434 978-784-6001 • www.bms.com 715 Diversified specialty biopharmaceuticals for oncology, cardiovascular, immunoscience and fibrosis Giovanni Caforio CEO 1858 9 GE Healthcare Life Sciences (d) 350 Campus Drive, Marlborough 01752 508-475-2000 • www.gelifesciences.com 700 Contrast agents for diagnostic imaging, basic research of cells and proteins and the technologies that enable large-scale manufacturing of vaccines, biologics, cell and gene therapies Emmanuel Ligner president & CEO 2004 9 KARL STORZ Endoscopy-America Inc. (e) 91 Carpenter Hill Road, Charlton 01507 508-248-9011 • www.karlstorz.com 700 Endoscopes, medical instruments and devices Charles Wilhelm president & COO 1989 9 Tegra Medical 9 Forge Parkway, Franklin 02038 508-541-4200 • www.tegramedical.com 700 Precision machining and contract manufacturing for medical device components J. Mark King president & CEO 2007 12 Sunovion Pharmaceuticals Inc. 84 Waterford Drive, Marlborough 01752 508-481-6700 • www.sunovion.com 603 Pharmaceuticals Nobuhiko Tamura chairman & CEO 2010 13 Olympus Surgical Technologies America 136 Turnpike Road, Southborough 01772 508-804-2600 • www.olympus-osta.com 369 Diagnostic and therapeutic endoscopes, advanced energy based hand instruments, sterile single-use devices and implants for urology, gynecology, ear nose & throat and general surgery Joe Doherty president, America Randy Clark group vice president, Medical Systems 2008 14 PerkinElmer Inc. 68 Elm St., Hopkinton 01748 781-663-6900 • www.perkinelmer.com 350 Lab instruments, software, imaging, informatics and services Robert Friel chairman & CEO 1937 15 SMC Ltd. 18 Independence Drive, Devens 01434 978-422-6800 • www.smcltd.com 300 Contract manufacturing for medical and drug delivery devices Brian Payson general manager & VP 1988 16 Nitto Denko Avecia Biotechnology Inc. (f) 125 Fortune Blvd., Milford 01757 508-532-2500 • www.avecia.com 240 Drug development and manufacturing services for oligonucleotide therapeutics Detlef Rethage president 1999 (g) 17 Pall Corp., Biotech Center of Excellence 20 Walkup Drive, Westborough 01581 508-871-5400 • www.pall.com 214 High-tech filtration, separation and purification for life sciences and industry Jennifer Honeycutt president, Pall 1946 18 Johnson Matthey Pharma Services (h) 25 Patton Road, Devens 01434 978-784-5000 • jmfinechemicals.com 200 Active pharmaceutical ingredients from preclinical through commercial production John B. Fowler fine chemicals division director 1972 18 Oxford Immunotec 700 Nickerson Road, Suite 200, Marlborough 01752 508-481-4648 • www.oxfordimmunotec.com 200 Proprietary tests for the management of under- served, immune-regulated conditions Peter Wrighton-Smith CEO 2002 20 Spectrum Plastics Group (i) 764 South Athol Road, Athol 01331 978-249-5343 • www.pexco.com 160 (e) Plastic profile and tubing extrusions for medical, fence and custom markets Neil Shillingford CEO 1948 21 Harvard Bioscience Inc. 84 October Hill Road, Holliston 01746 155 Laboratory research equipment Jeffrey A. Duchemin president & CEO 1901 18 Independence Drive, Devens 01434 978-422-6800 • www.smcltd.com 300 delivery devices general manager & VP 1988 16 Nitto Denko Avecia Biotechnology Inc. (f) 125 Fortune Blvd., Milford 01757 508-532-2500 • www.avecia.com 240 Drug development and manufacturing services for oligonucleotide therapeutics Detlef Rethage president 1999 (g) 17 Pall Corp., Biotech Center of Excellence 20 Walkup Drive, Westborough 01581 508-871-5400 • www.pall.com 214 High-tech filtration, separation and purification for life sciences and industry Jennifer Honeycutt president, Pall 1946 18 Johnson Matthey Pharma Services (h) 25 Patton Road, Devens 01434 978-784-5000 • jmfinechemicals.com 200 Active pharmaceutical ingredients from preclinical through commercial production John B. Fowler fine chemicals division director 1972 18 Oxford Immunotec 700 Nickerson Road, Suite 200, Marlborough 01752 508-481-4648 • www.oxfordimmunotec.com 200 Proprietary tests for the management of under- served, immune-regulated conditions Peter Wrighton-Smith CEO 2002 20 Spectrum Plastics Group (i) 764 South Athol Road, Athol 01331 978-249-5343 • www.pexco.com 160 (e) Plastic profile and tubing extrusions for medical, fence and custom markets Neil Shillingford CEO 1948 21 Harvard Bioscience Inc. 84 October Hill Road, Holliston 01746 508-893-8999 • www.harvardbioscience.com 155 Laboratory research equipment Jeffrey A. Duchemin president & CEO 1901 22 LFB USA & rEVO Biologics (j) 175 Crossing Blvd., Framingham 01702 508-620-9700 • www.lfb-usa.com 150 Biologics Jose Antonio Moreno Toscano CEO 1993 23 Astellas Institute for Regenerative Medicine (k) 33 Locke Drive, Marlborough 01752 508-756-1212 • www.astellas.us/therapeutic/rnd/ airm.aspx 120 Regenerative medicine and cell therapy research in ophthalmology and therapeutic areas that have few or no available treatment options Yoshitsugu Shitaka president 1994 (l) 24 SCIEX 500 Old Connecticut Path, Framingham 01701 877-740-2129 • www.sciex.com 103 Analytical technologies for life sciences Inese Lowenstein president 1970 25 Biomedical Research Models Inc. dba Biomere (e) 57 Union St., Worcester 01608 508-459-7544 • www.brmcro.com 70 Preclinical contract research Dennis L. Guberski president & chairman Mark Nedelman CEO 1996 26 CardioFocus Inc. 500 Nickerson Road, Suite 500-200, Marlborough 01752 508-658-7200 • www.cardiofocus.com 65 Tools for electrophysiologists for the treatment of atrial fibrillation Paul LaViolette executive chairman 1990 27 Hamilton Storage (m) 3 Forge Parkway, Franklin 02038 508-544-7000 • www.hamilton-storage.com 50 (e) Design and manufacture of liquid handling, process measurement, robotics and sample storage solutions Matt Hamilton president 1998 27 Optim LLC (n) 64 Technology Park Road, Sturbridge 01566 508-347-5100 • www.optimnet.com 50 Flexible fiberoptic endoscopes and assemblies Douglas Hughes president & CEO 1971 29 Allurion Technologies 14 Huron Drive, Natick 01760 508-647-4000 • www.allurion.com 37 Procedureless medical device for weight loss Shantanu Gaur (o) co-founder & CEO 2009 30 21st Century Biochemicals Inc. 260 Cedar Hill St., Marlborough 01752 508-303-8222 • www.21stcenturybio.com 25 Manufacturer of custom biochemicals for medical research Jordan B. Fishman president & CEO 2003 31 MustangBio (p) Plantation St., Worcester 01605 781-652-4500 • www.mustangbio.com 20 Development of cancer treatments Manual Litchman president 2015 32 SBH Sciences Inc. 4 Strathmore Road, Natick 01760 508-650-6200 • www.SBHSciences.com 18 Recombinant cytokines, cell-based assays and biomarker services Raphael Nir president & CSO 1997 33 Psychemedics Corp. 125 Nagog Park, Acton 01720 978-206-8220 • www.psychemedics.com 12 Manufacturer of drug tests Raymond C. Kubacki chairman, president & CEO 1987 34 NuVascular Technologies Inc. 200 Homer Ave., Ashland 01721 508-881-8860 • www.nuvasculartech.com 10 Artificial blood vessels, heart products, as well as products to treat end-stage renal disease Matthew D. Phaneuf co-founder and chairman 2014 35 Alzheon 111 Speen St., Suite 306, Framingham 01701 508-861-7709 • alzheon.com 9 Therapeutics for Alzheimer's and other neurological disorders Martin Tolar president & CEO 2013 36 Interscope Inc. 100 Grove St., Suite 108, Worcester 01605 877-420-7299 • www.interscopemed.com 8 Novel interventional endoscopic techniques and commercialization of proprietary EndoRotor platform to advance the practice of interventional gastroenterology and pulmonology Jeffery Ryan Jr. co-founder, president & CEO 2011 37 BioSurfaces Inc. 200 Homer Ave., Ashland 01721 508-881-8860 • www.biosurfaces.us 5 Nanotechnology to augment existing medical care and emerging approaches Matthew D. Phaneuf president & CTO 2003 Via two of its subsidiaries, Holliston life-science firm Harvard Bioscience has launched two new programs aimed at studying the brain and diabetes treatment. The launches, announced in May, include subsidiaries Data Sciences International (DSI) and Multi Channel Systems (MCS). DSI, a Minnesota-based firm acquired by Harvard in March for $70 million, has launched two telemetry implants the company hopes will meet the needs of neu - roscience researchers focused on large animal models. The implants are designed to acquire data from conscious, freely moving laborato- ry animals to provide stress-free data collection while enhancing animal welfare, the company said. The company eyes research gains in numerous areas of study, including sleep, seizure, affective disorders, movement disorders and neurodegenerative disorders. DSI's related technology has already been adopted by cardio - vascular researchers, said Harvard Bioscience President and CEO Jeffrey Duchemin. MCS' Beta Cell-System, a screening tool for diabetes research, uses multi-electrode array technology to take non-inva - sive measurements from small clusters of cells in the pancreas that the company hopes can sup- port the development of new drugs to treat type 2 diabetes and for further research. Duchemin in a statement said the system will help researchers discover new diabetes treatments and better understand the dis - ease. "With this product, MCS enters a new segment of the electro- physiology market," he said. Harvard Bioscience working on brain, diabetes research devices Harvard Bioscience President and CEO Jeffrey Duchemin

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