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74 Worcester Business Journal | Book of Lists 2018 | wbjournal.com F O C U S M A N U F A C T U R I N G & T E C H N O L O G Y Top biomedical companies Ranked by number of local employees Company Local employees Products Head of company Year founded 1 Sanofi Genzyme (a) 15 Pleasant St. Connector, Framingham 01701 508-872-8400 • www.sanofigenzyme.com 1,800 Biotechnology Bill Sibold executive vice president 1981 2 Boston Scientific Corp. 300 Boston Scientific Way, Marlborough 01752 508-683-5670 • www.bostonscientific.com 1,700 Medical devices Michael F. Mahoney president & CEO 1979 3 Waters Corp. 34 Maple St., Milford 01757 508-482-2000 • www.waters.com 1,500 Analytical science technologies Christopher J. O'Connell chairman, president & CEO 1958 4 Quest Diagnostics Inc. 200 Forest St., Marlborough 01752 866-697-8378 • www.questdiagnostics.com 1,450 (b) Diagnostic information services Steve Rusckowski president & CEO 1967 5 Hologic Inc. 250 Campus Drive, Marlborough 01752 508-263-2900 • www.hologic.com 1,245 Medical devices Stephen P. MacMillan president & CEO 1985 6 Integrated Genetics (LabCorp) 3400 Computer Drive, Westborough 01581 508-898-9001 • www.integratedgenetics.com ~1,000 (c) Healthcare diagnostics David P. King president & CEO 1991 7 AbbVie Inc. 100 Research Drive, Worcester 01605 508-849-2500 • www.abbvie.com 900 Biopharmaceutical therapies targeted at immunology, oncology, virology and neuroscience Richard A. Gonzalez chairman & CEO 2013 8 Bristol-Myers Squibb Co. 38 Jackson Road, Devens 01434 978-784-6001 • www.bms.com 715 Diversified specialty biopharmaceuticals for oncology, cardiovascular, immunoscience and fibrosis Giovanni Caforio CEO 1858 9 GE Healthcare Life Sciences (d) 350 Campus Drive, Marlborough 01752 508-475-2000 • www.gelifesciences.com 700 Contrast agents for diagnostic imaging, basic research of cells and proteins and the technologies that enable large-scale manufacturing of vaccines, biologics, cell and gene therapies Emmanuel Ligner president & CEO 2004 9 KARL STORZ Endoscopy-America Inc. (e) 91 Carpenter Hill Road, Charlton 01507 508-248-9011 • www.karlstorz.com 700 Endoscopes, medical instruments and devices Charles Wilhelm president & COO 1989 9 Tegra Medical 9 Forge Parkway, Franklin 02038 508-541-4200 • www.tegramedical.com 700 Precision machining and contract manufacturing for medical device components J. Mark King president & CEO 2007 12 Sunovion Pharmaceuticals Inc. 84 Waterford Drive, Marlborough 01752 508-481-6700 • www.sunovion.com 603 Pharmaceuticals Nobuhiko Tamura chairman & CEO 2010 13 Olympus Surgical Technologies America 136 Turnpike Road, Southborough 01772 508-804-2600 • www.olympus-osta.com 369 Diagnostic and therapeutic endoscopes, advanced energy based hand instruments, sterile single-use devices and implants for urology, gynecology, ear nose & throat and general surgery Joe Doherty president, America Randy Clark group vice president, Medical Systems 2008 14 PerkinElmer Inc. 68 Elm St., Hopkinton 01748 781-663-6900 • www.perkinelmer.com 350 Lab instruments, software, imaging, informatics and services Robert Friel chairman & CEO 1937 15 SMC Ltd. 18 Independence Drive, Devens 01434 978-422-6800 • www.smcltd.com 300 Contract manufacturing for medical and drug delivery devices Brian Payson general manager & VP 1988 16 Nitto Denko Avecia Biotechnology Inc. (f) 125 Fortune Blvd., Milford 01757 508-532-2500 • www.avecia.com 240 Drug development and manufacturing services for oligonucleotide therapeutics Detlef Rethage president 1999 (g) 17 Pall Corp., Biotech Center of Excellence 20 Walkup Drive, Westborough 01581 508-871-5400 • www.pall.com 214 High-tech filtration, separation and purification for life sciences and industry Jennifer Honeycutt president, Pall 1946 18 Johnson Matthey Pharma Services (h) 25 Patton Road, Devens 01434 978-784-5000 • jmfinechemicals.com 200 Active pharmaceutical ingredients from preclinical through commercial production John B. Fowler fine chemicals division director 1972 18 Oxford Immunotec 700 Nickerson Road, Suite 200, Marlborough 01752 508-481-4648 • www.oxfordimmunotec.com 200 Proprietary tests for the management of under- served, immune-regulated conditions Peter Wrighton-Smith CEO 2002 French drugmaker Sanofi laid off 95 employees from its Framingham location in May. According to Bo Piela, head of communications at the Sanofi Genzyme subsidiary, the company is investing more than $300 mil - lion in new facilities and improved technology to transform the loca- tions' operations to prepare to produce new medicines. "This transformation at our Framingham sites will streamline our operations, and we are adjust - ing staffing levels at the site accordingly," Piela said. Affected employees will receive severance benefits and outplace- ment assistance. "We are fully committed to the city of Framingham, which has been an important center for our research and manufacturing activ - ity for nearly 30 years. Massachusetts will remain a criti- cal global hub for Sanofi for years to come," he said. The layoffs come as the com- pany is planning a nearly 15,000-square-foot, two-story expansion of its existing 101,000-square-foot plant on New York Avenue. According to planning docu - ments, the project will add $15 million in value to the property. The company laid off 130 Boston-based employees in February, and about 1,800 employees remain in Framingham. There are about 5,000 Sanofi employees working in Massachusetts, Piela said. Genzyme was acquired by Sanofi in 2011 for about $20 bil - lion. Sanofi lays off 95 Framingham workers Sanofi's Framingham offices