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wbjournal.com | Book of Lists 2017 | Worcester Business Journal 71 M A N U F A C T U R I N G & T E C H N O L O G Y F O C U S Top biomedical companies Ranked by number of local employees Company Local employees Products Head of company Year founded 1 Sanofi Genzyme 1 15 Pleasant St. Connector, Framingham 01701 508-872-8400 • www.sanofigenzyme.com 2,000 Biotechnology David Meeker president & CEO 1981 2 Waters Corp. 34 Maple St., Milford 01757 508-482-2000 • www.waters.com 1,500 Analytical science technologies Christopher J. O'Connell president & CEO 1958 3 Boston Scientific Corp. 300 Boston Scientific Way, Marlborough 01752 508-683-5670 • www.bostonscientific.com 1,471 Medical devices Michael F. Mahoney president & CEO 1979 4 Quest Diagnostics Inc. 200 Forest St., Marlborough 01752 866-697-8378 • www.questdiagnostics.com 1,200 2 Diagnostic information services Steve Rusckowski president & CEO 1997 5 Integrated Genetics (LabCorp) 3400 Computer Drive, Westborough 01581 508-898-9001 • www.integratedgenetics.com ~1,000 3 Healthcare diagnostics David P. King president & CEO 1991 6 AbbVie Inc. 100 Research Drive, Worcester 01605 508-849-2500 • www.abbvie.com 900 Biopharmaceuticals Richard A. Gonzalez chairman & CEO 2013 7 Hologic Inc. 250 Campus Drive, Marlborough 01752 508-263-2900 • www.hologic.com 854 Medical devices Stephen P. MacMillan president & CEO 1987 8 KARL STORZ Endoscopy-America Inc. 91 Carpenter Hill Road, Charlton 01507 800-421-0837 • www.karlstorz.com 700 Endoscopes, medical instruments and devices Charles Wilhelm president & COO 1989 8 Tegra Medical 9 Forge Parkway, Franklin 02038 508-541-4200 • www.tegramedical.com 700 Precision machining and contract manufacturing for medical device components J. Mark King president & CEO 2007 10 GE Healthcare Life Sciences 4 350 Campus Drive, Marlborough 01752 508-475-2000 • www.gelifesciences.com 680 Life sciences Kieran Murphy CEO 2004 11 Bristol-Myers Squibb Co. 38 Jackson Road, Devens 01434 978-784-6001 • www.bms.com 645 Diversified specialty biopharmaceuticals Giovanni Caforio CEO 1858 12 Sunovion Pharmaceuticals Inc. 84 Waterford Drive, Marlborough 01752 508-481-6700 • www.sunovion.com 619 Pharmaceuticals Nobuhiko Tamura vice chairman & president 2010 13 PerkinElmer Inc. 68 Elm St., Hopkinton 01748 781-663-6900 • www.perkinelmer.com 300 Lab instruments, software and services Robert Friel chairman & CEO 1937 14 Nitto Denko Avecia Biotechnology Inc. 5 125 Fortune Blvd., Milford 01757 508-532-2500 • www.avecia.com 290 Manufacturing of oligonucleotide drugs with services from pre-clinical through commercialization Hideo Takasaki president & CEO, Nitto Denko Corp. 1993 6 14 SMC Ltd. 18 Independence Drive, Devens 01434 978-422-6800 • www.smcltd.com 290 Supplies to medical device and pharmaceutical industries Brian Payson general manager & VP 1988 16 Olympus Surgical Technologies America 136 Turnpike Road, Southborough 01772 508-804-2600 • www.olympus-osta.com 250 Surgical and medical equipment Joe Doherty president 1908 17 Johnson Matthey Pharma Services 25 Patton Road, Devens 01434 978-784-5000 • jmfinechemicals.com 200 7 Active pharmaceutical ingredients from preclinical through commercial production John B. Fowler fine chemicals division director 1972 18 LFB USA & rEVO Biologics 8 175 Crossing Blvd., Framingham 01702 508-620-9700 • www.lfb-usa.com 185 Biotechnology company William Gavin president 1993 19 Spectrum Plastics Group 9 764 South Athol Road, Athol 01331 978-249-5343 • www.pexco.com 160 Plastic profile and tubing extrusions for medical, fence and custom markets Neil Shillingford CEO 1948 20 Harvard Bioscience Inc. 84 October Hill Road, Holliston 01746 508-893-8999 • www.harvardbioscience.com 150 Laboratory research equipment Jeffrey A. Duchemin president & CEO 1901 21 Oxford Immunotec 700 Nickerson Road, Suite 200, Marlborough 01752 508-481-4648 • www.oxfordimmunotec.com 135 Proprietary tests for the management of under- served, immune-regulated conditions Peter Wrighton-Smith CEO 2002 22 Astellas Institute for Regenerative Medicine 10 33 Locke Drive, Marlborough 01752 508-756-1212 • www.astellas.us/therapeutic/rnd/ 70 Regenerative medicine and cell therapy research in ophthalmology and therapeutic areas that have few or no available treatment options Yoshitsugu Shitaka president 1994 11 16 136 Turnpike Road, Southborough 01772 508-804-2600 • www.olympus-osta.com 250 Surgical and medical equipment Joe Doherty president 1908 17 Johnson Matthey Pharma Services 25 Patton Road, Devens 01434 978-784-5000 • jmfinechemicals.com 200 7 Active pharmaceutical ingredients from preclinical through commercial production John B. Fowler fine chemicals division director 1972 18 LFB USA & rEVO Biologics 8 175 Crossing Blvd., Framingham 01702 508-620-9700 • www.lfb-usa.com 185 Biotechnology company William Gavin president 1993 19 Spectrum Plastics Group 9 764 South Athol Road, Athol 01331 978-249-5343 • www.pexco.com 160 Plastic profile and tubing extrusions for medical, fence and custom markets Neil Shillingford CEO 1948 20 Harvard Bioscience Inc. 84 October Hill Road, Holliston 01746 508-893-8999 • www.harvardbioscience.com 150 Laboratory research equipment Jeffrey A. Duchemin president & CEO 1901 21 Oxford Immunotec 700 Nickerson Road, Suite 200, Marlborough 01752 508-481-4648 • www.oxfordimmunotec.com 135 Proprietary tests for the management of under- served, immune-regulated conditions Peter Wrighton-Smith CEO 2002 22 Astellas Institute for Regenerative Medicine 10 33 Locke Drive, Marlborough 01752 508-756-1212 • www.astellas.us/therapeutic/rnd/ airm.aspx 70 Regenerative medicine and cell therapy research in ophthalmology and therapeutic areas that have few or no available treatment options Yoshitsugu Shitaka president 1994 11 22 Biomedical Research Models Inc. d/b/a Biomere 57 Union St., Worcester 01608 508-459-7544 • www.brmcro.com 70 Preclinical contract research Dennis L. Guberski president & chairman Mark Nedelman CEO 1996 24 Hamilton Storage 12 3 Forge Parkway , Franklin 02038 508-544-7000 • www.hamilton-storage.com 50 Design and manufacture of liquid handling, process measurement, robotics and sample storage solutions Matt Hamilton president 1998 25 Biostage Inc. 13 84 October Hill Road, Holliston 01746 800-232-2380 • biostage.com 31 Regenerative medicine, stem cell therapy and tissue engineering James McGorry CEO 2013 26 Allurion Technologies 14 Huron Drive, Natick 01760 508-647-4000 • www.allurion.com 20 Medical device for weight loss Jonathan Wecker 2010 27 SBH Sciences Inc. 4 Strathmore Road, Natick 01760 508-650-6200 • www.SBHSciences.com 15 Cell-based discovery and preclinical process development services based on expertise in cell culture, biologic production and biomarker development Raphael Nir president & CSO 1997 28 Alzheon 111 Speen St., Suite 306, Framingham 01701 508-861-7709 • alzheon.com 9 Therapeutics for Alzheimer's and other neurological disorders Martin Tolar president & CEO 2013 29 Interscope Inc. 100 Grove St., Suite 108, Worcester 01605 877-420-7299 • www.interscopemed.com 7 Novel interventional endoscopic techniques and commercialization of proprietary EndoRotor platform to advance the practice of interventional gastroenterology and pulmonology Jeffery Ryan Jr. co-founder, president & CEO 2011 30 Biotricity Medical Inc. 17 Alexander Road, Hopkinton 01748 508-259-1554 • www.biotricitymedical.com 2 Epivolt, an implantable energy source using the body's' own cells to power implanted electrical devices such as pacemakers Stephen Rathmill president & co-founder 2007 Source: Each company via survey. Note: List includes companies in the biotech, medical device, medical equipment and pharmaceutical industries. Hudson, Wisc.-based Phillips-Medisize acquired Clinton's Injectronics Corp. in June 2016; unable to confirm information about the Clinton facility by press time. Wayland's Candela Corp., a subsidiary of Syneron Inc., was acquired by Apax Partners in April 2017; the company has not responded to the survey since 2015. Biocytogen LLC of Worcester declined to participate in the survey. Unable to confirm information for Acton's Psychemedics Corp., Accelovance of Hudson or Westborough's Pall Life Sciences/Danaher Corp. by press time. 1 Sanofi Genzyme is the specialty care global business unit of Sanofi. 2 Employee counts include Worcester's Athena Diagnostics, specialty division of Quest Diagnostics. 3 Local employee figure falls within a range of 1,000-4,999, according to data published by the Executive Office of Labor and Workforce Development. 4 Three facilities, including office and lab space, in Marlborough; one location in Westborough 5 An additional location in Marlborough 6 Founding year for Avecia Biotechnology 7 Data from 2016 survey 8 Formerly rEVO Biologics 9 Fomerly Pexco of Athol; merged with Alpharetta, Ga.-based PPC Industries, owned by Kohlberg & Co., effective May 9. 10 In Feb. 2016, acquired Ocata Therapeutics, which was formerly known as Advanced Cell Technology 11 Founding year for Advanced Cell Technology 12 Affiliate of Hamilton Co. 13 Harvard Apparatus Regenerative Technology Inc. (NASDAQ: HART), a spinoff from Harvard Bioscience, changed its corporate name to Biostage Inc. and trades under the symbol BSTG (Nasdaq) effective April 1, 2016. - Compiled by: Stephanie R. Meagher, smeagher@nebusinessmedia.com Top Massachusetts employers by job listings, 2016 Sanofi Genzyme: 2,934 Biogen: 1,926 Pfizer: 1,487 Takeda Pharmaceuticals: 1,284 Vertex Pharmaceuticals: 988 Merck & Company: 897 Novartis: 730 Bristol-Myers Squibb: 338 Quest Diagnostics: 336 Charles River Labs: 315 Alnylam: 274 Shire: 266 Amgen: 241 PerkinElmer: 223 Parexel: 208 Sunovion: 201 Ironwood Pharmaceuticals: 199 Danaher Corporation: 161 AbbVie: 156 Astrazeneca: 144 Source: Massachusetts Biotechnology Education Foundation 2017 annual job trends forecast.