Issue link: https://nebusinessmedia.uberflip.com/i/1544464
wbjournal.com | April 20, 2026 | Worcester Business Journal 17 Let's hit it out of the park together. Real estate loans Business term loans Business lines of credit clintonsavings.com Commerical Construction loans SBA 7A and 504 loans Call our All-Star Lending Team today at 978-365-3450. Top NIH grant winners Ranked by number of awards, then total funding in FY 2025 Organization Number of NIH awards Total NIH funding Largest NIH funded project/ largest NIH funded project value 1 UMass Chan Medical School Worcester 345 $190,361,290 Precision editing of granulin mutations that cause frontotemporal dementia $6,580,415 2 Cummings School of Veterinary Medicine at Tufts University North Grafton 19 $10,864,926 New England Regional Biosafety Laboratory $2,363,198 3 Worcester Polytechnic Institute Worcester 17 $12,255,472 Integrative mindfulness-based predictive approach for chronic low-back pain treatment $6,889,914 4 Kephera Diagnostics LLC Framingham 8 $5,217,123 Point-of-care diagnostic test for T. cruzi (Chagas) infection $1,015,000 5 Microbiotix Inc. Worcester 7 $8,231,947 Development of pan-filovirus therapeutics $2,938,788 6 Helixbind Inc. Boxborough 5 $5,074,337 Direct-from-specimen identification of pathogens common in endocarditis $1,049,999 7 Signablok Inc. Worcester 3 $1,444,302 First-in-class TREM-1 inhibitors for neovascular retinal diseases $830,491 8 Outcome Referrals Inc. Framingham 2 $1,824,045 Increasing access to quality behavioral health care $1,102,380 9 General Biophysics LLC Framingham 2 $450,000 Xenon gas inhalation as a novel treatment for opioid withdrawal syndrome $400,000 10 AutoIVF Inc. Sudbury 1 $997,028 Automated microfluidic oocyte retrieval and denudation device $997,028 11 Capesym Inc. Natick 1 $925,411 High-resolution direct-conversion X-ray detectors for low-dose imaging $925,411 12 AssayQuant Technologies Inc. Marlborough 1 $906,895 Activity-based sensor peptides for direct, high-throughput, and kinetic quantitation of oncogenic protein kinases in unfractionated cell and tissue samples $906,895 13 Bessor Pharma LLC Framingham 1 $903,732 Development of novel renalase agonist for the treatment of acute pancreatitis $903,732 14 CG Scientific Inc. Worcester 1 $833,381 Low-cost platform technology for rapid isolation of peripheral blood mononuclear cells $833,381 15 Cantata Bio LLC Worcester 1 $746,680 Commercialization of rapid, automated Hi-C platform for sensitive genomic profiling of multiple cancer sample types $746,680 16 Altec Inc. Natick 1 $690,901 Augmented reality platform for telehealth rehabilitation $690,901 17 Bluebird Photonics Inc. Wayland 1 $305,853 Novel light source development for robust multi-MHz retinal OCT $305,853 18 Institute For Future Intelligence Inc. Natick 1 $268,144 Integrating data science into the science curriculum $268,144 19 Acpharis Inc. Holliston 1 $202,467 Software for increased accuracy prediction of antibody-antigen complexes $202,467 Source: National Institutes of Health (NIH) Notes: In fiscal year 2025, NIH awarded 5,423 grants totaling $3.4 billion in funding statewide. Central Massachusetts organizations were awarded 418 grants totaling $242.5 million, which is 7.7% of awards and 7.13% of total funding statewide. -Compiled by: Stephanie R. Meagher, research@nebusinessmedia.com HEALTH CARE F O C U S