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HARTFORDBUSINESS.COM | NOVEMBER 17, 2025 27 The Lists LARGEST LIFE SCIENCES & BIOTECHNOLOGY COMPANIES IN CONNECTICUT Ranked by number of employees statewide Largest life sciences & biotechnology companies in Connecticut Ranked by number of employees statewide Company Conn.-based employees/ companywide Headquarters/ focus Ownership type/ ticker symbol Head of company/ year founded 1 Medtronic Inc. 60 Middletown Ave., North Haven 06473 203-492-5000; medtronic.com 3,000 (1) 95,000 Galway, Ireland Healthcare technology with treatments for 70 health conditions, cardiac devices, surgical robotics, insulin pumps, surgical tools, patient monitoring systems Public NYSE: MDT Geoffrey S. Martha CEO 1949 2 Inc. (2) 445 Eastern Point Road, Groton 06340 860-441-4100; .com 2,100 77,000 New York, N.Y. Pharmaceutical research, development and manufacturing Public NYSE: PFE Albert Bourla CEO 1849 3 Boehringer Ingelheim Pharmaceuticals Inc. 900 Ridgebury Road, 06877 203-798-9988; boehringer-ingelheim.us 2,000 54,500 Development and manufacturing of human healthcare products, especially in areas of unmet medical need Private Brian Hilberdink President, U.S. Human Pharma Jean-Michel Boers President, CEO & managing director, Boehringer Ingelheim USA 1885 4 Alexion, AstraZeneca Rare Disease 100 College St., New Haven 06510 475-230-2596; alexion.com 775 94,300 (3) Boston, Mass. Development & delivery of life-changing medicines for rare diseases Public NASDAQ: AZN Marc Dunoyer CEO 1992 5 CooperSurgical Inc. (4) 75 Corporate Drive, Trumbull 06611 203-601-5200; coopersurgical.com 609 3,328 Trumbull Development and commercialization of medical devices and diagnostics for women's health Public NASDAQ: COO (5) Holly Shef President 1990 6 The Jackson Laboratory for Genomic Medicine (6) 10 Discovery Drive, Farmington 06032 860-837-2474; jax.org 456 3,000 Bar Harbor, Maine Discovery of genomic causes of disease and development of diagnostics and therapeutics Non-pr Mark Adams ector 2014 (7) 7 Avna Inc. 200 Ellis St., New Britain 06051 860-225-8707; avna.com 320 480 New Britain Medical device manufacturing Private Jason M. Howey President & CEO 1911 8 TOMZ Corp. 47 Episcopal Road, Berlin 06037 860-829-0670; tomz.com 250 250 Berlin Medical device manufacturing Private Tom Matulaniec CEO 1988 9 MannKind Corp. 1 Casper St., Danbury 06810 203-798-8000; mannkindcorp.com 230 (8) 420 (8) Danbury Development and commercialization of inhaled therapeutic products and devices for endocrine and orphan lung diseases Public NASDAQ: MNKD Michael Castagna CEO 1991 10 Paragon Medical (9) 1146 Barnum Ave., Bridgeport 06610 203-336-0121; paragonmedical.com 200 2,000 Pierceton, Ind. Medical device manufacturing and components for robotic assisted surgery, endoscopy, minimally invasive surgery, drug delivery, cosmetic surgery Public NYSE: AME Matt Williams Vice president of operations 1991 11 170 Broad St., New London 06320 800-222-1087; shef 165 N/A New London Manufacturing, production and distibution of pharmaceuticals Private Jeffrey Davis President & CEO 1850 12 Arthur G. Russell 750 Clark Ave., Bristol 06010 860-583-4109; arthurgrussell.com 107 127 Bristol Medical device assembly Private Jason Ensminger President 1945 13 Quantum-Si Inc. 29 Business Park Drive, Branford 06405 866-688-7374; quantum-si.com 68 (10) 191 (10) Branford Life sciences and protein sequencing Public NASDAQ: QSI Jeff Hawkins CEO 2013 14 Celldex Therapeutics Inc. 545 Long Wharf Drive, New Haven 06511 203-483-3500; celldex.com 42 N/A Hampton, N.J. Immunotherapy, therapeutic antibodies, antibody drug conjugates, immune system modulators Public NASDAQ:CLDX Anthony Marucci President & CEO 2005 15 Precipio Inc. 4 Science Park, 3rd Floor, New Haven 06511 203-787-7888; precipiodx.com 40 100 New Haven Cancer diagnostics Public NASDAQ: PRPO Ilan Danieli CEO 2011 16 Trevi Therapeutics Inc. 195 Church St., New Haven 06510 203-304-2499; trevitherapeutics.com 34 N/A New Haven Clinical-stage biopharmaceutical company Public NASDAQ: TRVI Jennifer L. Good Co-founder, president & CEO 2011 17 Halda Therapeutics 115 Munson St., New Haven 06511 475-210-0212; haldatx.com 32 N/A New Haven Therapeutics for treatment of cancer and other diseases, with initial focus on prostate and breast cancer Private Christian Schade CEO 2019 18 Bexorg Inc. 290 Congress Ave., New Haven 06419 203-208-8945; bexorg.com 30 32 New Haven Central nervous system (CNS) drug discovery and development using integrated whole-human brain wet-lab and AI platform Private Zvonimir Vrselja CEO & co-founder 2021 18 BioXcel Therapeutics 555 Long Wharf Drive, 12th Floor, New Haven 06511 475-238-6837; bioxceltherapeutics.com 30 30 New Haven neuroscience Public NASDAQ: BTAI Vimal D. Mehta Co-founder, chairman & CEO 2017 20 NorthEast BioAnalytical Laboratories LLC (11) 35 Worth Ave., Hamden 06518 203-361-3780; nebiolab.com 27 N/A Amsterdam Bioanalytical services across all stages of drug development from discovery to clinical trials Private Ron Mays Laboratory director 2003 Source: Each company via survey as of Q3-Q4 2025, websites, press releases, annual 10-K reports and Labor Market Information database, Conn. Dept. of Labor. ess time for New Haven's Arvinas Inc., which reported 253 Conn.-based employees on its 2024 survey; the company laid off 92 Conn.-based employees in May 2025. PerkinElmer U.S. LLC plans to permanently close its Shelton manufacturing facility in 2026, accor . Layoffs began in November 2025. Stamford's Purdue Pharma announced 99% of its creditors supported its new Chapter 11 Plan of Reorganization in an October 2025 pr otein Sciences' headquarters at the end of 2024. Plainville's Innovative Medical Products Inc. and Stamford's GeneDx, formerly Sema4 Holdings Corp., no longer disclose employee counts. (1) According to IndustrySelect; Q4 2023 survey reported 2,500 employees. (2) Additional clinical research site in New Haven. (3) For AstraZeneca. (4) A wholly owned subsidiary of The Cooper Cos. with an additional location in Guilford. (5) For parent company, The Cooper Cos. (6) In October 2025, completed acquisition of nonpr ork Stem Cell Foundation with assumption of the foundation's operations, assets and 77 employees. (7) Year founded for the Farmington site; The Jackson Laboratory was founded in 1929. (8) Survey submitted before completion of the acquistion of Burlington, Mass.-based scPharmaceuticals. (9) Additional location at 75 Aircraft Road in Southington. (10) Data from 2024 survey. (11) Acquired by Amsterdam-based Normec in September 2025. -Compiled by Stephanie R. Meagher, research@nebusinessmedia.com For more lists, visit our website hartfordbusiness.com/data