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V O L . X X X I N O. X X I I 60 G I V I N G G U I D E 2 0 2 5 – 2 0 2 6 N O N P RO F I T P RO F I L E 2026 GOALS Building on more than 90 years of leadership in genetics and genomics, e Jackson Laboratory ( JAX) is entering a bold new chapter. In alliance with e New York Stem Cell Foundation, we are poised to transform disease research and accelerate the discovery of life-changing therapies. In 2025 and 2026, our goals are clear: • Advance discoveries that will change outcomes for patients facing cancer, Alzheimer's disease, diabetes, Parkinson's disease and other urgent health challenges. • Educate and empower scientists at ever y stage — f rom high school students to early-career researchers — ensuring the next generation is equipped to lead. • Share our resources globally, enabling the scientific community to move faster, together. is is a pivotal moment for JAX — and for the future of human health. COMMUNITY IMPACT At JAX, we believe that science should serve humanity. From our home in Maine to communities around the world, we are accelerating breakthroughs that bring hope to patients and families. By integrating genetics, genomics, disease modeling and bioinformatics, JAX is driving progress across a wide spectrum of diseases including age- related conditions, Alzheimer's disease, cancer, cardiovascular disorders, diabetes and neurodegenerative diseases. Our research is not confined to the lab; it is designed to change lives. Education is central to our mission. For over a century, JAX has launched and advanced the careers of tens of thou- sands of learners. Our Clinical Education programs equip health care providers to use genetic and genomic information in patient care – from identifying who should be tested to interpreting results and guiding treatment decisions. In Maine, Teaching the Genome Gen- eration (TtGG) has trained 107 teachers, representing 96 different schools and over 14,000 students who have benefit- ted from TtGG lessons and laboratory experiments. Our unique ability to engage learners from high school to practicing physicians sets JAX apart. Our commitment to education extends beyond the classroom. e JAX College Scholarship Program supports first- generation Maine students pursuing STEM-related degrees, helping to build a more innovative future. At JAX, we are not just imagining a healthier world – we are building it with the people of Maine, for the benefit of all. GIVING OPPORTUNITIES JAX is a nonprofit biomedical research institution where philanthropy accelerates scientific research, discovery and educa- tion. Charitable gifts – including estate gifts – provide our scientists the flexibility to pursue bold, innovative approaches in their research as they advance treatments and cures for human disease. Your support also helps us train and educate scientists at every stage of their careers who are committed to building a healthier, more hopeful future. Join us today and be part of the next great breakthrough. Learn more about donating to JAX by email- ing advancement@jax.org, calling (800) 474-9880 or visiting www.jax.org/give. VOLUNTEER OPPORTUNITIES JAX welcomes volunteers to the Maine State Science Fair, managed by JAX and the Maine Mathematics and Science Alliance. e science fair encourages high school students to submit a science or engineering project and volunteers with STEM expertise are needed to judge at the event. The Jackson Laboratory BOARD OFFICERS Dan Hoag Corporate Secretary Douglas Abbott Treasurer BOARD MEMBERS Thomas C. Barry Otis W. Brawley, M.D. Joshua Broder Carla E. Brodley, Ph.D. Roger Crandall Timothy Dattels Jeffrey M. Friedman, M.D., Ph.D. Melissa Guzy Stewart J. Hen Eric Horvitz, M.D., Ph.D. George Montgomery Jenny Rooke, Ph.D. Janet Rossant, Ph.D., FRS, FRSC Dinakar Singh Geoffrey W. Smith, J.D. Sandra Elaine Waite, J.D. Mary Kate Wold, J.D. Lon Cardon, Ph.D., FMedSci President and CEO Neal B. Milch, J.D. Board Chair Established: 1929 / Employees: 2,837 / Annual revenue: $658M TOP FUNDING SOURCES 78% Genetic resources and clinical/ research services 18% Grants and philanthropic gifts 4% Investment return CONTACT 600 Main St., Bar Harbor, ME 04609 (207) 288-6000 www.jax.org jacksonlab.bsky.social JacksonLaboratory jaxlab jacksonlaboratory jacksonlab AWARDS/ACCOLADES 2025: LuAnn Ballesteros, vice president, external and government affairs, honored as one of three The Junior Achievement of Maine Business Hall of Fame Laureates. 2024: • JAX Cancer Center's National Cancer Institute designation renewed with the highest rating of 'exceptional,' marking its best score since 1983. • Leah Graham, program director of the Laboratory's Maine Cancer Genomics Initiative, earned Mainebiz's 40 Under 40 award. • Mary Dickinson, executive vice president and chief scientific officer, joined the ranks of Fellow of the American Association for the Advancement of Science. • Charles Lee, professor and Robert Alvine Family Endowed Chair, elected to the Royal Society of Canada. • LuAnn Ballesteros awarded the Maine Development Foundation's Kenneth M. Curtis Leadership Award. • JAX awarded the Ellsworth Chamber of Commerce's 2024 President's Award. MISSION STATEMENT We discover precise genomic solutions for disease and empower the global biomedical community in our shared quest to improve human health. MAINE LOCATIONS Bar Harbor, Ellsworth and Portland. AT A GLANCE