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wbjournal.com | April 15, 2024 | Worcester Business Journal 21 FOR ANY SIZE BUSINESS We have you covered Simply Beter. Member FDIC Member DIF Call one of our experienced commercial lenders at 800-649-3036 or email us at commercial@saversbank.com. H E A L T H C A R E & L I F E S C I E N C E S F O C U S Top NIH grant winners Ranked by number of awards, then total funding in FY 2023 Organization Number of NIH awards Total NIH funding Largest NIH funded project/ largest NIH funded project value 1 UMass Chan Medical School Worcester 353 $178,572,402 University of Massachusetts Center for Clinical and Translational Science (UMCCTS) $5,145,053 2 Worcester Polytechnic Institute Worcester 16 $6,683,438 Machine learning to predict pain response in patients with chronic lower back pain $1,643,228 3 Helixbind Inc. Boxborough 7 $7,041,282 Diagnostic tool for assessment and tracking of microbial load in bloodstream infections $1,050,000 4 Microbiotix Inc. Worcester 5 $4,460,198 Development of antibody drug conjugates as pan-filo antivirals $2,069,416 5 Kephera Diagnostics LLC Framingham 5 $4,359,007 Simple and specific one-tier assay for Lyme disease $1,025,000 6 Altec Inc. Natick 5 $3,551,714 Virtual reality platform for quantitative telehealth rehabilitation of rare diseases $1,713,818 7 Alzheon Inc. Framingham 2 $6,925,000 Randomized, double-blind, placebo-controlled phase 3 study for drug development in treatment of Alzheimer's disease $6,500,000 8 AutoIVF Inc. Sudbury 2 $1,885,360 OvaSafe microfluidic device enabling automated oocyte vitrification $1,069,950 9 Liberating Technologies Inc. Holliston 2 $1,438,770 Development of bimodal walking-running prosthetic foot $1,142,863 10 Biosurfaces Ashland 2 $1,160,484 Development of cell culture inserts and 3D in-vitro tissue models with novel electrospun scaffolds $884,718 11 Pacdna LLC Natick 2 $1,085,054 Molecular brush-conjugated antisense oligonucleotide as a pan-KRAS depletion agent $1,030,054 12 Signablok Inc. Worcester 2 $550,868 First-in-class TREM-1 inhibitors for neovascular retinal diseases $278,127 13 General Biophysics LLC Wayland 1 $1,318,445 Phase 1 trial to assesse safety and immune effects of Xenon gas in healthy human subjects $1,318,445 14 Bridge12 Technologies Inc. Framingham 1 $642,724 Benchtop Q-Band pulsed EPR spectrometer for intermolecular distance measurements $642,724 15 CG Scientific Inc. Worcester 1 $499,992 Automated system for high-yield pancreatic islet isolation $499,992 16 Pioneer Neurotech Inc. Sudbury 1 $422,015 Controlled gradient release of biologics with enhanced nerve conduit for long-gap injury repair $422,015 17 Codomax Inc. Worcester 1 $324,999 Exploiting translation elongation for improved biologics manufacturing $324,999 18 Luciole Pharmaceuticals Inc. Sherborn 1 $303,509 Discovery and development of OGG1 activators as precision drugs for modication of Alzheimer's disease progression $303,509 19 Bessor Pharma LLC Framingham 1 $299,999 New target and new therapy for severe COVID-19 and viral hyperinflammation damage $299,999 20 Outcome Referrals Inc. Framingham 1 $274,787 Consumer-therapist connector to increase access to quality behavioral healthcare $274,787 21 Institute For Future Intelligence Inc. Natick 1 $271,190 Integration of data science into science curriculum $271,190 22 Clark University Worcester 1 $98,045 Study of anti-viral role of HERC5 to aid in development of future viral treatments $98,045 23 International Society Of Vaccines Worcester 1 $5,000 International Society for Vaccines (ISV) Annual Congress, October 2023 in Lausanne, Switzerland $5,000 Source: National Institutes of Health (NIH) Notes: In fiscal year 2023, NIH awarded 5,920 grants totaling $3.5 billion in funding to 196 organizations statewide. Central Massachusetts organizations were awarded 414 grants totaling $222.2 million, which is 7% of awards and 6.3% of total funding statewide. -Compiled by: Stephanie R. Meagher, research@nebusinessmedia.com