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Central MA Life Sciences Report

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Central MA Life Sciences Report 21 AbbVie, a national biotech company headquartered in Illinois, with offices in Worcester, where it developed Humira, the most financially successful drug in history. Available and emerging technology will change how researchers can understand disease and analyze data, said Schwartz Sterman. She estimates it might be the biggest moment in scientific research since the Human Genome Project. World leader in gene therapy UMass Chan Medical School in Worcester may be the flagship for innovative research in the region as one of the leading recipients of National Institutes of Health grant funding in the state, even when accounting for the amount of money Greater Boston companies and universities pull. In fiscal year 2022, the school received $180 million across 349 NIH grants, according to NIH data compiled by the Worcester Business Journal Research Department. That total far surpasses any other institution in Central Massachusetts. By comparison, Worcester Polytechnic Institute, with the second highest number of grants at 15, pulled in $4.6 million in NIH funding. Gene therapy, a division of medical science aiming to repair or modify cells to produce a therapeutic effect in the treatment of disease, is a thriving area of research at UMass Chan. Guangping Gao, co-director of the Li Weibo Institute for Rare Diseases Research, director of the Horae Gene Therapy Center, and professor of microbiology and physiological systems at UMass Chan, has been involved in gene therapy research for decades. Gao cited the 15 faculty members in numerous labs working with a multitude of postdocs and technicians as a basis for saying that the medical school is a world leader in gene therapy. "When you add it all together, I don't think anywhere else in the country has this. It's the next generation of gene therapy medicine," said Gao. Annette Schwartz Sterman (right) leads immunology discovery at AbbVie in Worcester. Continued on page 22

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