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wbjournal.com | Book of Lists 2022 | Worcester Business Journal 41 M A N U F A C T U R I N G F O C U S Largest biomedical companies Ranked by number of local employees Company Local employees/ worldwide employees/ revenue Focus or products Chief executive(s)/ year founded 1 Waters Corp. 34 Maple St., Milford 01757 508-482-2000 • www.waters.com 1,600 7,500 $2,730,000,000 Analytical science technologies Udit Batra president & CEO 1958 2 Insulet Corp. 100 Nagog Park, Acton 01720 978-600-7000 • www.insulet.com 1,145 2,248 $904,400,000 Medical devices targeting diabetes Shacey Petrovic president & CEO 2000 3 Bristol Myers Squibb 38 Jackson Road, Devens 01434 978-784-6001 • www.bms.com 1,100 32,200 $46,385,000,000 Medicines for patients with serious diseases Giovanni Caforio chairman & CEO 1887 4 Quest Diagnostics 200 Forest St., Marlborough 01752 866-697-8378 • www.QuestDiagnostics.com 1,082 50,000 $10,788,000,000 Diagnostic information services Steve Rusckowski chairman, CEO & president 1967 5 Boston Scientific Corp. 300 Boston Scientific Way, Marlborough 01752 508-683-5670 • www.bostonscientific.com 1,000 (1) 41,000 $11,900,000,000 (2) Medical devices Michael F. Mahoney president 1979 5 Jabil 101 Union St., Clinton 01510 978-365-9721 • www.jabil.com 1,000 260,000 $27,266,438,000 Medical devices for diabetes care, drug delivery and injectables Mark Mondello CEO 1966 7 AbbVie Inc. 100 Research Drive, Worcester 01605 508-849-2500 • www.abbvie.com 997 48,000 $56,122,000,000 Biopharmaceuticals targeting various health issues; products for Allergan Aesthetics portfolio Richard A. Gonzalez chairman & CEO 2013 8 Hologic Inc. 250 Campus Drive, Marlborough 01752 508-263-2900 • www.hologic.com 983 7,129 $3,776,400,000 Medical devices Stephen P. MacMillan chairman, president & CEO 1985 9 Cytiva 350 Campus Drive, Marlborough 01752 508-475-2000 • www.cytiva.com 800 10,000 DND Life sciences and biotherapeutics Emmanuel Ligner president 2004 10 KARL STORZ Endovision Inc. 91 Carpenter Hill Road, Charlton 01507 508-248-9011 • www.karlstorz.com 700 8,500 DND Endoscopes, medical instruments and devices Bruce Watkins president & general manager 1989 11 Sunovion Pharmaceuticals Inc. 84 Waterford Drive, Marlborough 01752 508-481-6700 • www.sunovion.com 500 1,200 DND Pharmaceuticals Antony Loebel president & CEO 2010 12 Integrated Genetics (Labcorp) 3400 Computer Drive, Westborough 01581 508-898-9001 • www.integratedgenetics.com 436 (3) 72,410 (4) DND Healthcare diagnostics Adam Schechter president & CEO, Labcorp 1991 13 Tegra Medical 9 Forge Parkway, Franklin 02038 508-541-4200 • www.tegramedical.com 433 (3) 993 (3) DND Contract manufacturing of complex components and complete medical devices Walter Kobler CEO 2007 14 Olympus Corp. of the Americas 800 West Park Drive, Westborough 01581 508-804-2600 • www.olympusamerica.com 429 31,653 $5,860,000,000 Endoscopes, laparoscopes, video imaging systems, surgical energy devices, system integration solutions, medical services and endotherapy instruments Jorge Lopes president, Olympus Surgical Technologies America Julien Sauvagnargues president, Olympus Corp. of the Americas 1968 15 SMC Ltd. 18 Independence Drive, Devens 01434 978-422-6800 • www.smcltd.com 400 2,000 DND Contract manufacturing for medical and drug delivery devices Brian Payson VP & general manager 1988 16 PerkinElmer Inc. 68 Elm St., Hopkinton 01748 781-663-6900 • www.perkinelmer.com 303 (5) 16,000 $5,067,000,000 Solutions to serve the diagnostics, life sciences, food and applied markets Prahlad Singh president & CEO 1937 17 Nitto Denko Avecia Inc. 125 Fortune Blvd., Milford 01757 508-532-2500 • www.avecia.com 300 (6) 500 DND Drug development and manufacturing services for oligonucleotide therapeutics Seiji Fujioka president 1999 18 KARL STORZ Endoscopy America Inc. 28 Millbury St., Auburn 01501 508-248-9011 • www.karlstorz.com 230 8,500 DND Endoscopes, medical instruments and devices John O'Keefe executive director, supply chain operations 1989 19 Cogmedix, a Coghlin Co. (7) 127 Hartwell St., West Boylston 01583 800-640-3760 • www.cogmedix.com 200 200 DND Medical device product development and manufacturing Chris Coghlin president & CEO 2008 20 Astellas Institute for Regenerative Medicine 9 Technology Drive, Westborough 01581 508-756-1212 • www.astellas.com 190 17,000 DND Regenerative medicine and cell therapy research in ophthalmology and other therapeutic areas Masahide Goto president 1994 21 Harvard Bioscience Inc. 84 October Hill Road, Holliston 01746 508-893-8999 • www.harvardbioscience.com 155 464 DND Laboratory research equipment James Green president & CEO 1901 22 Akoya Biosciences Inc. 100 Campus Drive, 6th Floor, Marlborough 01752 855.896.8401 • www.akoyabio.com 154 319 $54,900,000 Spatial biology platform preserving spatial context of whole tissues, mapping how cells organize to influence disease outcomes Brian McKelligon CEO 2015 23 Hamilton Storage (8) 3 Forge Parkway, Franklin 02038 508-544-7000 • www.hamilton-storage.com 125 125 DND Design and manufacture of liquid handling, process measurement, robotics and sample storage solutions John Genereux vice president Matt Hamilton president 1998 24 Mustang Bio Inc. (9) 377 Plantation St., Worcester 01605 781-652-4500 • www.mustangbio.com 120 120 DND Development of cell and gene therapies Manuel Litchman president & CEO 2015 25 Curia Global (10) 35 South St., Hopkinton 01748 (11) 888-406-5658 • www.curiaglobal.com 106 3,700 DND Contract research and manufacturing services John Ratliff CEO 1991 26 Baxter (12) 100 Discovery Way, Acton 01720 978-263-5401 • www.baxter.com 100 50,000 DND Medical device and technology innovator Jose Almeida CEO 1931 26 Biomere 57 Union St., Worcester 01608 508-459-7544 • www.biomere.com 100 (13) DND Preclinical contract research Mark Nedelman CEO 1996 26 SCIEX 100 Life science analytical technologies, Joe Fox 20 9 Technology Drive, Westborough 01581 508-756-1212 • www.astellas.com DND therapeutic areas 1994 21 Harvard Bioscience Inc. 84 October Hill Road, Holliston 01746 508-893-8999 • www.harvardbioscience.com 155 464 DND Laboratory research equipment James Green president & CEO 1901 22 Akoya Biosciences Inc. 100 Campus Drive, 6th Floor, Marlborough 01752 855.896.8401 • www.akoyabio.com 154 319 $54,900,000 Spatial biology platform preserving spatial context of whole tissues, mapping how cells organize to influence disease outcomes Brian McKelligon CEO 2015 23 Hamilton Storage (8) 3 Forge Parkway, Franklin 02038 508-544-7000 • www.hamilton-storage.com 125 125 DND Design and manufacture of liquid handling, process measurement, robotics and sample storage solutions John Genereux vice president Matt Hamilton president 1998 24 Mustang Bio Inc. (9) 377 Plantation St., Worcester 01605 781-652-4500 • www.mustangbio.com 120 120 DND Development of cell and gene therapies Manuel Litchman president & CEO 2015 25 Curia Global (10) 35 South St., Hopkinton 01748 (11) 888-406-5658 • www.curiaglobal.com 106 3,700 DND Contract research and manufacturing services John Ratliff CEO 1991 26 Baxter (12) 100 Discovery Way, Acton 01720 978-263-5401 • www.baxter.com 100 50,000 DND Medical device and technology innovator Jose Almeida CEO 1931 26 Biomere 57 Union St., Worcester 01608 508-459-7544 • www.biomere.com 100 (13) DND Preclinical contract research Mark Nedelman CEO 1996 26 SCIEX 500 Old Connecticut Path, Framingham 01701 877-740-2129 • www.sciex.com 100 3,000 DND Life science analytical technologies, precision detection and quantification of molecules Joe Fox president 1970 26 vivitide (14) 65 Zub Lane, Gardner 01440 978-630-0020 • www.vivitide.com 100 100 DND Designer and producer of custom peptides and antibodies for drug and vaccine discovery in life science industry Martina Diekmann CEO 1998 30 BMP Medical 16 Chocksett Road, Suite 2, Sterling 01564 978-632-2555 • www.bmpmedical.com 90 90 DND Engineering, consulting and injection molded medical supplies for medical industry Mike Faulkner president & CEO 1978 31 Lykan Bioscience 97 South St., Hopkinton 01748 774-341-4200 • www,lykanbio.com 67 71 DND Process development and manufacturing for autologous and allogeneic cell-based therapies Patrick Lucy president & CEO 2019 32 Mevion Medical Systems Inc. 300 Foster St., Littleton 01460 978-540-1500 • www.mevion.com 64 314 DND Design, manufacture, install and service proton beam radiotherapy (PBRT) system services for cancer treatment Tina Yu CEO 2004 33 Vibalogics U.S. Inc. 1414 Massachusetts Ave., Boxborough 01719 351-277-4800 • www.vibalogics.com 60 150 DND Contract development and manufacturing organization (CDMO) focusing on complex live biological products Tom Hochuli CEO 2019 34 Eppendorf North America Inc. 100 Crossing Blvd., Framingham 01702 800-645-3050 • www.eppendorf.com 50 (15) 5,000 DND Developer of instruments, consumables, and services for liquid-, sample-, and cell handling in laboratories Dennis Barger president, Eppendorf Americas 1945 34 Veristat 134 Turnpike Road, Suite 200, Southborough 01772 508-429-7340 • www.veristat.com 50 600 DND Contract research organization (CRO) with focus on strategy, clinical trial design and implementation, data analysis, and marketing applications Patrick Flanagan CEO 1994 34 YMC America Inc. (16) 8 Charlestown St., Devens 01434 978-487-1000 • www.ymcpt.com 50 500 DND Process engineering firm Rich Howard controller Mark Dyment president & CEO 2000 37 Microbiotix One Innovation Drive, Worcester 01605 508-757-2800 • www.microbiotix.com 25 25 DND Novel small molecule drugs for infectious diseases such as multi-drug resistant pathogens; lead program targets adenoviral conjunctivitis Terry Bowlin president & CEO 1998 37 StageBio 450 Donald Lynch Blvd., Marlborough 01752 513-204-4400 • www.stagebio.com 25 250 DND Provider of preclinical and clinical histology, pathology and specimen archiving services Lori Ball CEO 1999 39 Psychemedics Corp. 289 Great Road, Acton 01720 978-206-8220 • www.psychemedics.com 12 200 (17) DND R&D and lab services to detect drugs by hair analysis; FDA-cleared for cocaine, opioids, amphetamines, PCP, THC, fentanyl, benzodiazepines, and more Raymond C. Kubacki 1987 40 BioSurfaces LLC 200 Homer Ave., Unit 1P, Ashland 01721 508-881-8860 • www.biosurfaces.us 11 11 DND Medical devices using proprietary electrospinning process Tina M. Phaneuf VP finance Matthew D. Phaneuf president & CTO 2003 40 Bluejay Diagnostics Inc. 360 Massachusetts Ave., Suite 203, Acton 01720 978-631-4884 • www.bluejaydx.com 11 11 DND Diagnostics and medical devices Neil Dey CEO 2015 40 Verax Biomedical Inc. 148 Bartlett St., Marlborough 01752 508-755-7029 • www.veraxbiomedical.com 11 21 DND Testing systems for detecting bacterial contamination in cells James Lousararian CEO 1999 Source: Each company via survey. Contact research@nebusinessmedia.com to be surveyed for this or other lists. (1) Local employee figure falls within a range of 1,000-4,999 according to data provided by Mass. Executive Office of Labor and Workforce Development. (2) Net sales (3) Figure from 2021 survey (4) Figure from 2021 survey, represents global employee count for Labcorp (5) Data include Oxford, U.K.-based Oxford Immunotec, a PerkinElmer company, with a location in Marlborough. (6) Local employee count falls within a range of 300-350 according to data provided by Mass. Executive Office of Labor and Workforce Development. (7) In February 2022, broke ground on new $8.7-million facility, which will double headquarters and create 200 new jobs over next five years. (8) Affiliate of Hamilton Co. (9) Subsidiary of New York-based Fortress Biotech (10) Formerly LakePharma, acquired by Curia Global in 2021 (11) With an additional Central Mass. location at 50 Prescott St., Worcester (12) Formerly Hillrom. IL-based Baxter International Inc. completed acquisition of Hillrom in Dec. 2021. (13) As reported to editorial staff May 2021 (14) Formerly New England Peptide Inc. (15) Estimate per WBJ editorial staff as of October 2020. (16) Formerly Integrated Process Technologies Inc. (17) Count fluctuates between 200 and 250. -Compiled by: Heide Martin, hmartin@nebusinessmedia.com In November, Lykan Bioscience announced plans to expand its facility in Hopkinton by 1,700 square feet to increase its clinical and commercial manufacturing capacity by 90%. The project received a 14-year property tax break from the Town of Hopkinton, bringing $4.5 million in value. BMP Medical moved from Gardner to its 80,000-square-foot facility in Sterling in 2019. In July, the Mevion's S250i Proton Therapy System was used by a cancer patient for the first time at Mercy Hospital St. Louis in Missouri, one of 40 such treating centers in the U.S. The compact size of the system enables hospitals to better integrate the technology into existing radiation oncology departments. In August, YMC expanded its national facilities with a 3,500-square-foot building next to its headquarters in Devens, along with a separate smaller expansion in California. The company uses the new space for separation studies and other research. In January, StageBio appointed Lori Ball as its new CEO, succeeding Tom Galati, former CEO and founder. Before joining StageBio, Ball was chief operating officer at New York life sciences firm BioIVT.