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16 Worcester Business Journal | April 18, 2022 | wbjournal.com Top NIH grant winners Fiscal 2021 grants, ranked by total funding Company Total NIH funding FY 2021 Number of NIH awards FY 2021 Largest NIH funded project FY 2021 Largest NIH funded project value FY 2021 1 UMass Chan Medical School Worcester $170,455,068 358 University of Massachusetts Center for Clinical and Translational Science (UMCCTS) $5,148,876 2 Alzheon Framingham $12,500,000 1 Randomized, double-blind, placebo-controlled, phase 3 study of Alzheimer's disease oral treatment $12,500,000 3 Microbiotix Worcester $6,966,418 10 Oxadiazole inhibitors of non-stop ribosome rescue to treat MDR meisseria gonorrhoeae $1,052,607 4 Helixbind Inc. Marlborough $4,992,384 5 An integrated device for rapid bacteremia diagnosis direct from whole blood (1) $1,000,000 5 Worcester Polytechnic Institute Worcester $4,132,408 13 MR-guided precision conformal ablation therapy for brain tumors $706,183 6 Kephera Diagnostics LLC Framingham $3,589,259 4 In-vitro diagnostic for the liver flukes opisthorchis viverrini and clonorchis sinensi $1,999,961 7 Bridge12 Technologies Inc. Framingham $3,061,452 4 A high-power, broadband 395 GHz gyrotron amplifier for DNP-NMR and EPR spectroscopy $1,519,798 8 Curadel LLC Natick $2,342,505 2 ZW800-1: The 1st zwitterionic NIR fluorophore for cancer imaging & ureter mapping $1,595,693 9 Zata Pharmaceuticals Inc. Worcester $1,886,885 2 A closed system for pathogen reduction of red blood cells for transfusion $1,169,287 10 Bessor Pharma LLC Framingham $1,327,758 1 Novel target, new therapy: anti-renalase antibody for tumors resistant to PD-1 inhibitors $1,327,758 11 Altec Inc. Natick $1,175,596 3 EMG voice restoration $563,939 12 Mustang Bio Inc. (2) Worcester $999,336 1 A phase 1, open-label, multicenter trial to assess the safety, tolerability and efficacy of MB-106 in patients with relapsed or refractory CD20+ B-Cell NHL or CLL $999,336 13 Nirogyone Therapeautics Natick $854,530 1 Development of tumor and immuno-metabolism based small molecule therapeutics for refractory breast cancer $854,530 14 Enrich Therapeutics Inc. Worcester $829,125 1 Single clone discovery using an image-based cell isolation platform $829,125 15 CG Scientific Inc. Worcester $749,988 1 Automated system for high-yield pancreatic islet isolation $749,988 16 Capesym Inc. Natick $732,292 1 Low-cost, low-dose flat panel X-ray detectors with a novel semiconductor $732,292 Source: National Institutes of Health data (1) Four projects received $1 million each. (2) Subsidiary of New York-based Fortress Biotech -Compiled by: Timothy Doyle, tdoyle@nebusinessmedia.com LO KING Many of our doctors are welcoming new patients. Meet them at reliantmedicalgroup.org. for a new doctor? F O C U S H E A L T H C A R E