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56 HARTFORDBUSINESS.COM | DECEMBER 27, 2021 Largest bioscience/biotechnology companies in Connecticut (Ranked by number of employees as of October 2021) Largest bioscience/biotechnology companies in Connecticut (Ranked by number of employees as of October 2021) Rank Company No. CT employees/ No. worldwide employees Headquarters/ Focus Ownership/ Ticker Top executive/ Year founded 1 Pfizer Inc. 558 Eastern Point Road Groton, CT 06340 (a) 860-441-4100; www.pfizer.com 2,700 (b) 78,500 New York, NY Pharmaceutical research, development and manufacturing Public NYSE: PFE Albert Bourla CEO 1849 2 Boehringer Ingelheim Pharmaceuticals Inc. 900 Ridgebury Road Ridgefield, CT 06877 203-798-9988; boehringer-ingelheim.us 2,600 9,000 Ridgefield, CT Development and manufacturer of human healthcare products especially in the areas of unmet medical need Private Jean-Michel Boers President, CEO, & U.S. country managing director, Boehringer Ingelheim USA 1885 3 Medtronic Inc. 60 Middletown Ave. North Haven, CT 06473 203-492-5000; www.medtronic.com 2,500 90,000 Dublin, Ireland Development, manufacturing and sales of surgical staplers Public NYSE: MDT Geoffrey S. Martha CEO 1949 4 Sema4 1 Commercial St. Branford, CT 06405 800-298-6470; sema4.com 634 1,148 Stamford Patient-centered health intelligence company leveraging AI and machine learning to derive data-driven insights Public NASDAQ: SMFR Eric Schadt Founder & CEO 2017 5 Alexion Pharmaceuticals Inc. (c) 100 College St. New Haven, CT 06510 475-230-2596; alexion.com 500 3,800 Cambridge, United Kingdom Severe and life-threatening rare disorders Public NASDAQ: AZN Marc Dunoyer CEO, Alexion and CFO, AstraZeneca 1992 6 Jackson Laboratory for Genomic Medicine 10 Discovery Drive Farmington, CT 06032 860-837-2474; www.jax.org 450 2,626 Bar Harbor, ME Discovery of genomic causes of disease and development of diagnostics and therapeutics Nonprofit DND Charles Lee Scientific director 2014 (d) 7 PerkinElmer Inc. 710 Bridgeport Ave. Shelton, CT 06484 (e) 203-925-4600; www.perkinelmer.com 396 14,000 Waltham, MA Detection, imaging, informatics, software and services innovating for a healthier world Public NYSE: PKI Prahlad Singh CEO 1937 8 Hologic Inc. 36 Apple Ridge Road Danbury, CT 06810 203-207-4500; www.hologic.com 326 6,900 Marlborough, MA Diagnostic, medical imaging and surgical products for women's healthcare Public NASDAQ: HOLX Stephen P. MacMillan Chairman, president & CEO 1986 9 CooperSurgical Inc. (f) 75 Corporate Drive Trumbull, CT 06611 203-601-5200; www.coopersurgical.com 250 (g) 12,000 (h) Trumbull Development and commercialization of medical devices and diagnostics for women's health Public NYSE: COO (i) Holly Sheffield President 1990 10 Arvinas Inc. 5 Science Park, 395 Winchester Ave. New Haven, CT 06511 203-535-1456; www.arvinas.com 216 216 New Haven Development of therapeutics to treat a variety of diseases including cancer, pro-inflammatory, autoimmune and rare disease Public NASDAQ: ARVN John Houston President & CEO 2013 11 MannKind Corporation 1 Casper St. Danbury, CT 06810 203-798-8000; www.mannkindcorp.com 190 340 Westlake Village, CA Development and commercialization of inhaled therapeutic products for patients with endocrine and orphan lung diseases Public NASDAQ: MNKD Michael Castagna CEO 1991 12 TOMZ Corp. 47 Episcopal Road Berlin, CT 06037 860-829-0670; www.tomz.com 180 190 Berlin Medical device manufacturer Private Tom Matulaniec President 1988 13 Biohaven Pharmaceutical Holding Co. 215 Church St. New Haven, CT 06510 203-404-0410; biohavenpharma.com 100 900 New Haven Neuroscience Public NYSE: BHVN Vlad Coric CEO 2013 13 Protein Sciences, a division of Sanofi 1000 Research Parkway Meriden, CT 06450 203-427-2403; www.sanofi.com 100 100,000 (j) Paris, France Vaccine development and protein production Public NASDAQ: SNY (k) Paul Hudson CEO, Sanofi 1994 15 Quantum-Si Inc. 520 Old Whitfield St. Guilford, CT 06437 203-458-7100; www.quantum-si.com 80 121 Guilford Life sciences; protein sequencing Public NASDAQ: QSI John Stark CEO 2013 16 CARA Therapeutics 107 Elm St., 9th Floor, 4 Stamford Plaza Stamford, CT 06902 203-406-3700; www.caratherapeutics.com 59 82 Stamford Development of therapeutics to treat human diseases associated with pruritus Public NASDAQ: CARA Derek Chalmers Director, president & CEO 2004 17 BioXcel Therapeutics 555 Long Wharf Drive New Haven, CT 06511 475-238-6837; bioxceltherapeutics.com 50 83 New Haven Biopharmaceutical firm using artificial intelligence to advance development of medicines for neuroscience, immuno-oncology and other diseases Public NASDAQ: BTAI Vimal D. Mehta Founder & CEO 2017 18 BioSig Technologies Inc. 55 Greens Farms Road Westport, CT 06880 203-409-5444; www.biosig.com 49 DND Westport Bioelectronic medicine Public NASDAQ: BSGM Kenneth L. Londoner CEO 2009 19 Precipio Inc. 4 Science Park, 3rd Floor New Haven, CT 06511 203-787-7888; www.precipiodx.com 40 60 New Haven Genetic testing Public NASDAQ: PRPO Ilan Danieli CEO 2017 (l) 20 Tangen Biosciences Inc. 20 Commercial St. Branford, CT 06405 203-433-4045; tangenbiosciences.com 33 33 Branford Molecular diagnostics Private Richard C. Birkmeyer President & CEO 2013 21 Rallybio Corporation 234 Church St., Suite 1020 New Haven, CT 06510 203-859-3820; rallybio.com 31 31 New Haven Identifying and accelerating the development of transformative therapies for patients with severe and rare disorders Public (m) NASDAQ: RLYB Martin Mackay Co-founder & CEO 2018 22 Oxford Performance Materials Inc. 30 S. Satellite Road South Windsor, CT 06074 860-698-9300; www.oxfordpm.com 30 30 South Windsor Patient implant solutions as well as materials technology for other industries Private Scott DeFelice President & CEO 2000 23 Celldex Therapeutics Inc. 300 George St., Suite 530 New Haven, CT 06511 203-483-3500; celldex.com 25 125 (n) Hampton, NJ Immunotherapy, therapeutic antibodies, antibody drug conjugates, immune system modulators Public NASDAQ:CLDX Anthony Marucci President & CEO 2005 24 Cybrexa Therapeutics 5 Science Park, 395 Winchester Ave. New Haven, CT 06511 860-717-2731; cybrexa.com 23 23 New Haven Development of therapies using Alphalex platform to deliver anti-cancer agents directly into tumor cells Private Per Hellsund President & CEO 2017 Sources: Each company via survey, website and/or press releases, annual 10-K reports to SEC and Labor Market Information database, Conn. Dept of Labor. Notes: N/A = not available or not applicable. In August 2020, Clinton-based Ce3 merged into North Carolina-based Catalyst Clinical Research; local employee count could not be confirmed. (a) With an additional Conn. site in New Haven. (b) Plus an additional 2,700 contractors assigned to CT sites. (c) A subsidiary of AstraZeneca. (d) Year founded for the Farmington site. The Jackson Laboratory was founded in 1929. (e) With an additional R&D operation in Branford. (f) A wholly owned subsidiary of The Cooper Companies. (g) Number of employees is 250-499 according to CT Department of Labor, Labor Market Information. (h) As of October 31, 2020 as reported to SEC, form 10-K. (i) For parent company, The Cooper Companies. (j) Greater than 100,000 worldwide, Sanofi. (k) For parent company Sanofi S.A. based in Paris, France. (l) Year founded as a result of the merger with Transgenomics Inc. (m) On Aug. 2, 2021, announced closing of initial public offering of public shares with the U.S. Securities & Exchange Commission. (n) As of Dec. 2020, per SEC 10-K filing FY ending Dec. 31, 2020. —Compiled by Heide Martin. HEALTH