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Book of Lists 2021

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HEALTH CARE 74 | BOOK OF LISTS 2021 LARGEST BIOSCIENCE/BIOTECHNOLOGY COMPANIES IN CONNECTICUT (Ranked by number of employees) Largest bioscience/biotechnology companies in Connecticut (Ranked by number of employees) Rank Company No. CT employees/ Headquarters Focus Ownership/ Ticker Top executive/ Year founded 1 Pfizer Inc. 558 Eastern Point Road Groton, CT 06340 860-441-4100; www.pfizer.com 2,700 (a) New York, NY Pharmaceutical research, development and manufacturing Public NYSE: PFE Albert Bourla CEO 1849 2 Boehringer Ingelheim Pharmaceuticals Inc. 900 Ridgebury Road Ridgefield, CT 06877 203-798-9988; boehringer-ingelheim.us 2,100 Ridgefield, CT Development and manufacturer of human healthcare products especially in the area of unmet medical need Private Jean-Michel Boers President, CEO, & U.S. country managing director, Boehringer Ingelheim USA Corp. 1885 3 Medtronic Inc. 60 Middletown Ave. North Haven, CT 06473 203-492-5000; www.medtronic.com 1,500 Dublin, Ireland Development, manufacturing and sales of surgical staplers Public NYSE: MDT Geoffrey S. Martha CEO 1949 4 Alexion Pharmaceuticals Inc. (b) 100 College St. New Haven, CT 06510 475-230-2596; alexion.com 500 Boston, Mass. Severe and life-threatening rare disorders Public NASDAQ: ALXN Ludwig N. Hantson CEO 1992 4 PerkinElmer Inc. 710 Bridgeport Ave. Shelton, CT 06484 (c) 203-925-4600; www.perkinelmer.com 500 (d) Waltham, Mass. Detection, imaging, informatics, software and services innovating for a healthier world Public NYSE: PKI Prahlad Singh CEO (e) 1937 6 The Jackson Laboratory for Genomic Medicine 10 Discovery Drive Farmington, CT 06032 860-837-2474; www.jax.org 400 Bar Harbor, ME Discovery of genomic causes of disease and development of diagnostics and therapeutics Nonprofit Charles Lee Scientific director 2014 (f) 7 Sema4 1 Commercial St. Branford, CT 06405 800-298-6470; sema4.com 300 Stamford Patient-centered health intelligence for reproductive health and oncology Private Eric Schadt Founder & CEO 2017 8 Hologic Inc. 36 Apple Ridge Road Danbury, CT 06810 203-207-4500; www.hologic.com 287 Marlborough, MA Diagnostic, medical imaging, and surgical products for women's healthcare Public NASDAQ: HOLX Stephen P. MacMillan Chairman, president & CEO 1986 9 Arvinas Inc. 5 Science Park, 395 Winchester Ave. New Haven, CT 06511 203-535-1456; www.arvinas.com 170 New Haven Development of therapeutics to treat a variety of diseases including cancer, pro- inflammatory, autoimmune and rare disease Public NASDAQ: ARVN John Houston President & CEO 2013 10 MannKind Corporation 1 Casper St. Danbury, CT 06810 203-798-8000; www.mannkindcorp.com 103 Westlake Village, CA Development and commercialization of inhaled therapeutic products for patients with endocrine and orphan lung diseases Public NASDAQ: MNKD Michael Castagna CEO 1991 11 Biohaven Pharmaceutical Holding Co. LTD 215 Church St. New Haven, CT 06510 203-404-0410; biohavenpharma.com 87 New Haven Neuroscience Public NYSE: BHVN Vlad Coric CEO 2013 12 Sanofi Pasteur 1000 Research Parkway Meriden, CT 06450 203-427-2403; www.sanofi.com 71 (g) Swiftwater, Pa. Vaccine development and protein production Public NASDAQ: SNY (h) Paul Hudson CEO 1994 13 Ce3 Inc. 6 Post Office Square Clinton, CT 06413 203-404-7500; www.ce3inc.com 67 Clinton Contract research focused on providing biotechnology companies with phase 1 and phase 2 clinical trial execution, primarily in oncology, and regulatory submission services Private Holly Ohanesian Coulter President & CEO 2005 14 CARA Therapeutics 107 Elm St., 9th Floor, 4 Stamford Plaza Stamford, CT 06902 203-406-3700; www.caratherapeutics.com 60 Stamford Development of therapeutics to treat human diseases associated with pruritus, pain and inflammation Public NASDAQ: CARA Derek Chalmers Director, president & CEO 2004 15 Tangen Biosciences Inc. 20 Commercial St. Branford, CT 06405 203-433-4045; tangenbio.com 32 Branford Molecular diagnostics Private Richard C. Birkmeyer President and CEO 2013 16 Celldex Therapeutics Inc. 300 George St., Suite 530 New Haven, CT 06511 203-483-3500; celldex.com 25 (i) Hampton, N.J. Immunotherapy, therapeutic antibodies, antibody drug conjugates, immune system modulators Public NASDAQ:CLDX Anthony Marucci President & CEO 2005 17 BioXcel Therapeutics 555 Long Wharf Drive New Haven, CT 06511 475-238-6837; bioxceltherapeutics.com 24 (j) New Haven Biopharmaceutical firm using artificial intelligence to advance development of medicines for neuroscience, immuno-oncology and other diseases Public NASDAQ: BTAI Vimal D. Mehta Founder & CEO 2017 18 CooperSurgical Inc. (k) 95 Corporate Dr. Trumbull, CT 06611 203-601-5200; www.coopersurgical.com 20 (l) Trumbull Development and commercialization of medical devices and diagnostics for women's health Public NYSE: COO Robert Auerbach President 1990 18 Cybrexa Therapeutics 5 Science Park, 395 Winchester Ave. New Haven, CT 06511 860-717-2731; cybrexa.com 20 New Haven Development of therapies using Alphalex platform to deliver anti-cancer agents directly into tumor cells Private Per Hellsund President & CEO 2017 18 Kleo Pharmaceuticals Inc. 25 Science Park, Suite 235 New Haven, CT 06511 203-691-6361; www.kleopharmaceuticals.com 20 New Haven Creation of fully synthetic compounds that recruit the immune system to destroy cancer cells Private Douglas Manion CEO 2015 18 New England Discovery Partners (m) 23 Business Park Drive Branford, CT 06405 203-208-2523; nedp.com 20 (l) Branford Contract research in synthetic and medicinal chemistry; drug discovery services to academic, pharmaceutical and biotechnology companies Private Michael Van Zandt President & CEO 2012 18 Rallybio 234 Church St., Suite 1020 New Haven, CT 06510 203-859-3820; rallybio.com 20 New Haven Developer of life-transforming therapies for patients with severe and rare disorders Private Martin Mackay co-founder & CEO 2018 23 Azitra Inc. 21 Business Park Drive Branford, CT 06405 203-646-6446; azitrainc.com 19 Branford, CT Clinical-stage medical dermatology company addressing serious skin conditions by harnessing the microbiome Private Richard Andrews CEO 2014 24 Innovative Medical Products Inc. 87 Spring Lane Plainville, CT 06062 860-793-0391; www.impmedical.com 18 Plainville, CT Design manufacture and sale of patient positioning devices for surgical procedures in hospitals and ambulatory surgery centers Private Alan A. Wasley CEO 1983 Source: Each company via survey. (a) Plus an additional 2,700 contractors assigned to CT sites. (b) On Jan. 28, 2020, acquired Achillion Pharmaceuticals, previously headquarterd in Blue Bell, Penn., for $930 million. In November, 2019, Achillion reported 45 employees in New Haven. (c) With an additional R&D operation in Branford. (d) Number of employees in Conn. is 500-999 according to CT Dept. of Labor, Labor Market Information. (e) Succeeded Robert Friel upon his retirement, December 2019. (f) Year founded for the Farmington site. The Jackson Laboratory was founded in 1929. (g) Data from November 2019. (h) For parent company Sanofi S.A. based in Paris, France. (i) Data from 2018. (j) As of December 31, 2019, as reported to SEC, form 10-K. (k) A wholly owned subsidiary of The Cooper Companies. (l) Number of employees in Conn. is 20-49, according to CT Dept. of Labor, Labor Market Information. (m) In November 2019, acquired by N.J.-based Genesis Drug Discovery & Development (GD3), a member of Genesis Biotechnology Group. —Compiled by Heide Martin.

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