Worcester Business Journal

wbjournal.com | March 30, 2020 | Worcester Business Journal 13 H E A L T H C A R E F O C U S Top NIH grant winners in Central Mass. Fiscal year 2019 grants, ranked by total funding Grantee Total funding Number of awards Largest project/ funding 1 University of Massachusetts Medical School Worcester $155,485,455 345 Center for 3D Structure and Physics of the Genome $2,864,158 2 Microbiotix Inc. Worcester $5,566,186 9 Oxadiazole inhibitors of non-stop ribosome rescue to treat MDR Neisseria gonorrhoeae $1,100,543 3 Worcester Polytechnic Institute Worcester $3,408,721 10 MR-guided precision conformal ablation therapy for brain tumors $678,161 4 Embera Neurotherapeutics Inc. Sudbury $3,380,100 1 Novel combination therapy for treatment of cocaine-use disorder $3,380,100 5 Altec Inc. Natick $1,638,417 4 NeuroMAP system for clinical research $629,721 6 Biostage Inc. Holliston $1,103,346 1 A retrievable auto esophageal implant for long-gap esophageal atresia $1,103,346 7 College of the Holy Cross Worcester $1,084,931 3 Roles for altered WNT signaling and oxidative stress response pathways as primary driver of reduced reparative capacity in aging canine lung mesenchymal stromal cells $391,314 8 Helixbind Inc. Marlborough $1,000,000 1 Automated platform for direct-from-specimen identification of pathogens common in endocarditis $1,000,000 9 Bessor Pharma LLC Framingham $849,303 1 Renalase: development as an innovative new drug for acute pancreatitis $849,303 10 SignaBlok Inc. Worcester $801,644 2 First-in-class TREM-1 inhibitors in combination therapy for pancreatic cancer $799,560 * 11 Zata Pharmaceuticals Inc. Worcester $780,492 1 Closed system for pathogen reduction of red blood cells for transfusion $780,492 12 Cytosite Biopharma Inc. Sudbury $759,285 1 Clinical translation of a novel diagnostic agent to predict immunotherapy response in solid tumors $759,285 13 CG Scientific Inc. Worcester $749,990 1 Automated device for high yield mesenchymal stem cell extraction $749,990 14 Curadel LLC Marlborough $720,367 1 Mediastinal lymph node identification in lung cancer using NIR fluorescent VATS $720,367 15 MatTek Corp. Ashland $690,297 3 Validation of in-vitro human airway model for regulatory toxicity testing $241,361 16 Detectogen Inc. Westborough $651,346 1 Novel, non-invasive antigen detection assay for diagnosis of active visceral leishmaniasis $651,346 17 Liberating Technologies Inc. Holliston $645,076 1 Pointdexter: a prosthetic fingertip terminal device $645,076 18 Bridge12 Technologies Inc. Framingham $641,448 1 ODNP probe to study hydration dynamics in membrane protein $641,448 19 BYOMass Inc. Sudbury $599,716 2 Identification of bi-specific antibodies to inhibit GDF-15 and active A for anorexia-cachexia $299,871 20 Spatial Surgical LLC Shrewsbury $490,801 2 Development of a computer-guided orthopedic laser surgical system – vision and measurement $246,510 21 Gentuity Inc. Sudbury $328,628 1 Micro-imaging catheters for high-resolution, image-guided, endovascular repair of brain aneurysms $328,628 22 Nirogyone Therapeautics Worcester $292,210 1 Tumor and immune-metabolism based lactate transporter inhibitors for metastatic melanoma $292,210 Source: National Institutes of Health, www.nih.gov. Note: The NIH granted 5,548 awards worth $3.02 billion in funding in Massachusetts in FY 2019; 399 awards worth $182.7 million were granted in Central Mass. * The second grant was filed under the same title for $2,084. - Compiled by: Heide Martin, hmartin@nebusinessmedia.com Source: National Institutes of Health, www.nih.gov. Note: The NIH granted 5,548 awards worth $3.02 billion in funding in Massachusetts in FY 2019; 399 awards worth $182.7 million were granted in Central Mass. * The second grant was filed under the same title for $2,084. - Compiled by: Heide Martin, hmartin@nebusinessmedia.com Top NIH grant winners in Central Mass. Fiscal year 2019 grants, ranked by total funding LO KING Many of our doctors are welcoming new patients. Meet them at reliantmedicalgroup.org. for a new doctor?

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