Hartford Business Journal

February 10, 2020

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www.HartfordBusiness.com • February 10, 2020 • Hartford Business Journal 15 Source: Each company via survey. Notes: ADME = absorption, distribution, metabolism, and excretion. Hologic Inc., Medtronic and New Haven Pharmaceuticals do not disclose employee data by geographic location. AxioMx Inc. (Abcam plc), Becton Dickinson, Charles River Laboratories International Inc., CooperSurgical Inc., Gilead Connecticut Inc., Icahn School of Medicine Mount Sinai Genomics Research Center and IDEXX Laboratories were contacted but did not complete a survey. In September 2019 Stamford's Purdue Pharma LP and its subsidiaries have voluntarily filed petitions for reorganization under Chapter 11 of the U.S. Bankruptcy Code. (a) Succeeded Paul R. Fonteyne, effective March 1, 2018. (b) On Jan. 28, 2020, Alexion Pharmaceuticals, headquartered in Boston, Mass., acquired Achillion Pharmaceuticals of Blue Bell, Penn., for $930 million. (c) With an additional R&D operation in Branford. (d) Year founded for the Farmington site. The Jackson Laboratory was founded in 1929. (e) Paris-based Sanofi acquired Protein Sciences Corp., effective Aug. 28, 2017. (f) Founding year for Protein Sciences Corp. (g) Data from 2018. —Compiled by Heide Martin. THE LIST Largest bioscience/biotechnology companies in Connecticut Ranked by number of employees as of October 2019 FOCUS: HEALTH CARE Largest bioscience/biotechnology companies in Connecticut (Ranked by number of employees as of October 2019) Rank Company Headquarters No. of employees in CT Focus Top executive/ Year founded 1 Pfizer Inc. 558 Eastern Point Road Groton, CT 06340 860-441-4100; www.pfizer.com New York, NY 2,700 Pharmaceutical research, development and manufacturing Albert Bourla CEO 1849 2 Boehringer Ingelheim Pharmaceuticals Inc. 900 Ridgebury Road Ridgefield, CT 06877 203-798-9988; boehringer-ingelheim.us Ridgefield, CT 2,500 Development and manufacture of human and animal healthcare products Wolfgang Baiker (a) President & CEO 1885 3 Alexion Pharmaceuticals Inc. (b) 100 College St. New Haven, CT 06510 475-230-2596; alexion.com Boston, MA 500 Severe and life-threatening rare disorders Ludwig N. Hantson CEO 1992 3 PerkinElmer Inc. 710 Bridgeport Ave. Shelton, CT 06484 (c) 203-925-4600; www.perkinelmer.com Waltham, MA 500 Detection, imaging, informatics, software and services innovating for a healthier world Robert F. Friel Chairman & CEO 1937 5 The Jackson Laboratory for Genomic Medicine 10 Discovery Drive Farmington, CT 06032 860-837-2474; www.jax.org Bar Harbor, ME 372 Discovery of genomic causes of disease and development of diagnostics and therapeutics Charles Lee Scientific director 2014 (d) 6 Arvinas Inc. 5 Science Park New Haven, CT 06511 203-535-1456; www.arvinas.com New Haven, CT 132 Development of therapeutics to treat a variety of diseases including cancer, pro-inflammatory, autoimmune and rare disease John Houston President & CEO 2013 7 MannKind Corp. 1 Casper St. Danbury, CT 06810 203-798-8000; www.mannkindcorp.com Westlake Village, CA 102 Development and commercialization of inhaled therapeutic products for patients with diseases such as diabetes and pulmonary arterial hypertension Michael Castagna CEO 1991 8 Biohaven Pharmaceutical Holding Co. LTD 215 Church St. New Haven, CT 06510 203-404-0410; biohavenpharma.com New Haven, CT 100 Neuroscience Vlad Coric CEO 2013 9 Sanofi Pasteur (e) 1000 Research Parkway Meriden, CT 06450 203-427-2403; www.sanofi.us Swiftwater, PA 71 Vaccine development and protein production Paul Hudson CEO 1983 (f) 10 Ce3 Inc. 246 Goose Lane, Suite 202 Guilford, CT 06437 203-404-7500; www.ce3inc.com Clinton, CT 63 (g) Contract research focused on providing biotechnology companies with phase 1 and 2 clinical trial execution and regulatory submission services Holly Ohanesian Coulter President & CEO 2005 11 CARA Therapeutics 107 Elm St., 9th Floor, 4 Stamford Plaza Stamford, CT 06902 203-406-3700; www.caratherapeutics.com Stamford, CT 55 Development of therapeutics to treat human diseases associated with pruritus, pain and inflammation Derek Chalmers Director, president & CEO 2004 12 Innovative Medical Products Inc. 87 Spring Lane Plainville, CT 06062 860-793-0391; www.impmedical.com Plainville, CT 50 Design and manufacture of patient positioning devices for surgical procedures in hospitals and ambulatory surgery centers Alan Wasley CEO 1983 13 Achillion Pharmaceuticals (b) 300 George St. New Haven, CT 06511 203-624-7000; www.achillion.com Blue Bell, PA 45 Factor D immune system inhibitors Joe Truitt President & CEO 2000 14 Celldex Therapeutics Inc. 300 George St., Suite 530 New Haven, CT 06511 203-483-3500; celldex.com Hampton, NJ 25 (g) Immunotherapy, therapeutic antibodies, antibody drug conjugates, immune system modulators Anthony Marucci President & CEO 2005 15 Azitra Inc. 400 Farmington Ave., CB126 RM1836 Farmington, CT 06032 203-599-0700; azitrainc.com Farmington, CT 12 Clinical-stage medical dermatology company addressing serious skin conditions by harnessing the microbiome Richard Andrews CEO 2014 15 CaroGen Corp. 400 Farmington Ave. Farmington, CT 06032 203-815-5782; carogencorp.com Farmington, CT 12 Development of immunotherapy vaccines for infectious disease, cancer and the treatment of patients with chronic hepatitis B virus Bijan Almassian President & CEO 2012 17 BioPharmaWorks LLC 93 Shennecossett Road Groton, CT 06340 860-912-6101; biopharmaworks.com Groton, CT 11 Drug discovery, medicinal chemistry, structural biology, pharmacokinetics, ADME and process chemistry Bob Volkmann CSO 2015 18 Synovel Laboratory LLC 375 Morgan Lane, Unit 204B West Haven, CT 06516 203-545-9462; synovellab.com West Haven, CT 10 Medicinal and process chemistry support for biotech and pharmaceuticals companies, university and nonprofit organizations Ho-Yin Lo Founder & CEO 2014 19 Artificial Cell Technologies 5 Science Park, Suite 13 New Haven, CT 06511 203-772-3430; artificialcelltech.com New Haven, CT 8 Vaccine development Donald S. Masters President & CEO 2006 20 Clemente Associates 33 Harkness Drive Madison, CT 06443 203-421-4500; clemente-associates.com Madison, CT 3 Cell capture (animal and human) Henry J. Clemente CEO 1989 Source: Each company via survey. Notes: ADME = absorption, distribution, metabolism, and excretion. Hologic Inc., Medtronic and New Haven Pharmaceuticals do not disclose employee data by geographic location. AxioMx Inc. (Abcam plc), Becton Dickinson, Charles River Laboratories International Inc., CooperSurgical Inc., Gilead Connecticut Inc., Icahn School of Medicine Mount Sinai Genomics Research Center and IDEXX Laboratories were contacted but did not complete a survey. In September 2019 Stamford's Purdue Pharma LP and its subsidiaries have voluntarily filed petitions for reorganization under Chapter 11 of the U.S. Bankruptcy Code. (a) Succeeded Paul R. Fonteyne, effective March 1, 2018. (b) On Jan. 28, 2020, Alexion Pharmaceuticals, headquartered in Boston, Mass., acquired Achillion Pharmaceuticals of Blue Bell, Penn., for $930 million. (c) With an additional R&D operation in Branford. (d) Year founded for the Farmington site. The Jackson Laboratory was founded in 1929. (e) Paris-based Sanofi acquired Protein Sciences Corp., effective Aug. 28, 2017. (f) Founding year for Protein Sciences Corp. (g) Data from 2018. —Compiled by Heide Martin.

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