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68 Worcester Business Journal | Book of Lists 2019 | wbjournal.com F O C U S M A N U F A C T U R I N G & T E C H N O L O G Y Designed to look great on all your devices, our new site helps you get more informed and connected to Central Mass business Visit WBJournal.com to see what's new. WBJ Worcester Business Journal OUR NEW WEBSITE IS LIVE! Top biomedical companies Ranked by number of local employees Company Local employees Products Head of company Year founded 1 Sanofi Genzyme (a) 15 Pleasant St. Connector, Framingham 01701 508-872-8400 • www.sanofigenzyme.com 1,800 Biotechnology Bill Sibold executive vice president 1981 2 Boston Scientific Corp. 300 Boston Scientific Way, Marlborough 01752 508-683-5670 • www.bostonscientific.com ~1,700 (b) Medical devices Michael F. Mahoney president & CEO 1979 3 Waters Corp. 34 Maple St., Milford 01757 508-482-2000 • www.waters.com 1,506 Analytical science technologies Christopher J. O'Connell chairman, president & CEO 1958 4 Quest Diagnostics Inc. 200 Forest St., Marlborough 01752 866-697-8378 • www.questdiagnostics.com 1,300 Diagnostic information services Steve Rusckowski president & CEO 1967 5 Hologic Inc. 250 Campus Drive, Marlborough 01752 508-263-2900 • www.hologic.com 1,245 (b) Medical devices Stephen P. MacMillan president & CEO 1985 6 Integrated Genetics (LabCorp) 3400 Computer Drive, Westborough 01581 508-898-9001 • www.integratedgenetics.com ~1,000 (c) Healthcare diagnostics David P. King president & CEO 1991 7 AbbVie Inc. 100 Research Drive, Worcester 01605 508-849-2500 • www.abbvie.com 900 Research-driven biopharmaceuticals targeted at immunology, oncology, virology and neuroscience Richard A. Gonzalez chairman & CEO 2013 8 KARL STORZ Endovision Inc. 91 Carpenter Hill Road, Charlton 01507 508-248-9011 • www.karlstorz.com 850 Endoscopes, medical instruments and devices Bruce Watkins general manager 1989 8 Nypro, a Jabil Co. 101 Union St., Clinton 01510 978-365-9721 • www.nypro.com 850 Medical devices Steve Borges executive vice president & CEO Nypro Healthcare 1955 10 GE Healthcare Life Sciences (d) 350 Campus Drive, Marlborough 01752 508-475-2000 • www.gelifesciences.com 835 Contrast agents for diagnostic imaging, basic research of cells and proteins and the technologies that enable large-scale manufacturing of vaccines, biologics, cell and gene therapies Emmanuel Ligner president & CEO 2004 11 Bristol-Myers Squibb Co. 38 Jackson Road, Devens 01434 978-784-6001 • www.bms.com 798 Diversified specialty biopharmaceuticals for oncology, cardiovascular, immunoscience and fibrosis Giovanni Caforio CEO 1858 12 Sunovion Pharmaceuticals Inc. 84 Waterford Drive, Marlborough 01752 508-481-6700 • www.sunovion.com 587 Pharmaceuticals Antony Loebel president & CEO 2010 13 Tegra Medical 9 Forge Parkway, Franklin 02038 508-541-4200 • www.tegramedical.com 390 Contract manufacturer of complex components and complete, medical devices J. Mark King president & CEO 2007 14 SMC Ltd. 18 Independence Drive, Devens 01434 978-422-6800 • www.smcltd.com 300 Contract manufacturing for medical and drug delivery devices Brian Payson general manager & VP 1988 15 PerkinElmer Inc. 68 Elm St., Hopkinton 01748 781-663-6900 • www.perkinelmer.com 280 Detection and imaging instruments, assays, software and services Robert Friel chairman & CEO 1937 16 Olympus Surgical Technologies America 136 Turnpike Road, Southborough 01772 508-804-2600 • www.olympus-osta.com 256 Diagnostic and therapeutic endoscopes, advanced energy-based hand instruments, sterile single-use devices and implants for urology, gynecology, ear nose & throat and general surgery Randy Clark group vice president, Medical Systems Tomo Sakurai head of operations, OSTA 2008 17 Nitto Denko Avecia Biotechnology Inc. (e) 125 Fortune Blvd., Milford 01757 508-532-2500 • www.avecia.com 240 Drug development and manufacturing services for oligonucleotide therapeutics Detlef Rethage president 1999 (f) 18 KARL STORZ Endoscopy America Inc. 14 Mechanic St., Southbridge 01550 508-248-9011 • www.karlstorz.com 225 Endoscopes, medical instruments and devices John O'Keefe director of supply chain operations 1989 19 Pall Corp. (b) 20 Walkup Drive, Westborough 01581 508-871-5400 • www.pall.com 214 High-tech filtration, separation and purification for life sciences and industry Jennifer Honeycutt president 1946 20 Johnson Matthey Pharma Services (g) 508-303-8222 • www.21stcenturybio.com 33 SBH Sciences Inc. 4 Strathmore Road, Natick 01760 508-650-6200 • www.SBHSciences.com 17 Recombinant cytokines, cell-based assays and biomarker services Raphael Nir president & chief science officer 1997 34 Psychemedics Corp. 125 Nagog Park, Acton 01720 978-206-8220 • www.psychemedics.com 12 Manufacturer of drug tests Raymond C. Kubacki chairman, president & CEO 1987 35 Interscope Inc. 100 Grove St., Suite 108, Worcester 01605 877-420-7299 • www.interscopemed.com 10 Design, manufacture and distribution of therapeutic endoscopic instruments for gastroenterology, pulmonology and otolaryngology procedures Jeffery Ryan Jr. co-founder, president & CEO 2011 36 Alzheon 111 Speen St., Suite 306, Framingham 01701 508-861-7709 • alzheon.com 9 Therapeutics for Alzheimer's and other neurological disorders Martin Tolar president & CEO 2013 37 BioSurfaces Inc. 200 Homer Ave., Ashland 01721 508-881-8860 • www.biosurfaces.us 8 Medical devices using a proprietary electrospinning process, which augments existing medical care and emerging approaches Matthew D. Phaneuf president & CTO 2003 38 SignaBlok Inc. 60 Prescott St., Suite 113, Worcester 01605 203-505-3807 • www.signablok.com 3 Targeted immunotherapies for oncology, immunology and cardiovascular Alexander Sigalov president & CEO 2009 Source: Each company via survey. Note: List includes companies in the biotech, medical device, medical equipment and pharmaceutical industries. Hudson, Wisc.-based Phillips-Medisize acquired Clinton's Injectronics Corp. in June 2016; unable to confirm information about the Clinton facility. Wayland's Candela Corp., a subsidiary of Syneron Inc., was acquired by Apax Partners in April 2017; the company has not responded to the survey since 2015. Biocytogen LLC of Worcester and Ayer's Cambrooke Therapeutics declined to participate in the survey. Unable to confirm information for Franklin's Hamilton Storage, Accelovance of Hudson, Marlborough's AngioDynamics, Milford's SeraCare Life Sciences or Holliston's Biostage Inc. (delisted from the NASDAQ in fall 2017) by press time. (a) Sanofi Genzyme is the specialty care global business unit of Sanofi; data from 2018 survey (b) Data from 2018 survey (c) Local employee figure falls within a range of 1,000-4,999 according to data published by the Executive Office of Labor and Workforce Development. (d) GE's biopharmaceutical division was sold for $21 billion in February 2019. (e) Data from 2018 survey; an additional location in Marlborough (f) Founding year for Avecia Biotechnology (g) Local employee figure from 2016 survey; local employee figure falls within a range of 100-249 according to data published by the Executive Office of Labor and Workforce Development; conversion of revenue from pounds into dollars by IRS yearly currency exchange rate of .750. (h) In February 2016, acquired Ocata Therapeutics, which was formerly known as Advanced Cell Technology (i) Founding year for Advanced Cell Technology (j) Formerly rEVO Biologics; parent company is LFB Group, France. (k) Subsidiary of New York-based Fortress Biotech (l) Succeeded Jonathan Wecker, effective Jan. 1, 2018 - Compiled by: Stephanie R. Meagher, smeagher@nebusinessmedia.com Source: Each company via survey. Note: List includes companies in the biotech, medical device, medical equipment and pharmaceutical industries. Hudson, Wisc.- based Phillips-Medisize acquired Clinton's Injectronics Corp. in June 2016; unable to confirm information about the Clinton facility. Wayland's Candela Corp., a subsidiary of Syneron Inc., was acquired by Apax Partners in April 2017; the company has not responded to the survey since 2015. Biocytogen LLC of Worcester and Ayer's Cambrooke Therapeutics declined to participate in the survey. Unable to confirm information for Franklin's Hamilton Storage, Accelovance of Hudson, Marlborough's AngioDynamics, Milford's SeraCare Life Sciences or Holliston's Biostage Inc. (delisted from the NASDAQ in fall 2017) by press time. (a) Sanofi Genzyme is the specialty care global business unit of Sanofi; data from 2018 survey (b) Data from 2018 survey (c) Local employee figure falls within a range of 1,000-4,999 according to data published by the Executive Office of Labor and Workforce Development. (d) GE's biopharmaceutical division was sold for $21 billion in February 2019. (e) Data from 2018 survey; an additional location in Marlborough (f) Founding year for Avecia Biotechnology (g) Local employee figure from 2016 survey; local employee figure falls within a range of 100-249 according to data published by the Executive Office of Labor and Workforce Development; conversion of revenue from pounds into dollars by IRS yearly currency exchange rate of .750. (h) In February 2016, acquired Ocata Therapeutics, which was formerly known as Advanced Cell Technology (i) Founding year for Advanced Cell Technology (j) Formerly rEVO Biologics; parent company is LFB Group, France. (k) Subsidiary of New York-based Fortress Biotech (l) Succeeded Jonathan Wecker, effective Jan. 1, 2018 - Compiled by: Stephanie R. Meagher, smeagher@nebusinessmedia.com Knowledge + Experience + Trusted Advice. It all adds up. Large enough to serve the needs of most businesses and individuals; small enough to offer the personal attention you expect and deserve. Greenberg, Rosenblatt, Kull & Bitsoli, PC Certified Public Accountants 306 Main Street, Suite 400 • Worcester, MA 01608 508.791.0901 • www.grkb.com BioSurfaces Cofounder & CTO Matthew D. Phaneuf graduated from UMass Dartmouth in 1989 and now serves on its industrial advisory board for the Department of Bioengineering. SignaBlock CEO Alexander Sigalov has worked at MIT in Cambridge and UMass Medical School in Worcester. His Ph.D. is from Moscow State University in Russia.